磺胺二甲嘧啶钠的二阶导数差示脉冲极谱法定量研究  

Studies on Quantitative Determination of Sulfadimidine Sodium by Secondary Derivative Differential Pulse Polarography

作　　者：梁云爱 田兆兴 

机构地区：[1]山东省日照市药品检验所,日照276800 [2]山东省日照市中医院,日照276800

出　　处：《分析试验室》2000年第5期78-81,共4页Chinese Journal of Analysis Laboratory

摘　　要：立了磺酸二甲嘧啶钠的二阶导数差示脉冲极谱定量分析方法 ,磺胺二甲嘧啶钠在乙醇 - (硼酸 -氯化钾缓冲液 ) -水 (体积比 70∶ 2∶ 2 8)的底液中 ,于 -1 .560 V(vs.Ag/Ag Cl)处出现一良好的二阶导数差示脉冲极谱峰 ,磺胺二甲嘧啶钠浓度与其峰幅值在 0 .0 6～ 0 .6mmol· L-1范围内呈非常显著的线性关系 (p<0 .0 1 ) ,检出限为 9.2 n mol·L-1。A secondary derivative differential pulse polarography method was developed for the determination of sulfadimidine sodium and its preparation.In ethanol buffer of boric acid potassium chloride water(volume ratio 70∶2∶28) solution,sulfadimidine sodium showed a very good sencondary derivative differential pulse polarographic peak at -1.560 V( vs .Ag/AgCl).Linear relationship between concentration of sulfadimidine sodium and peak height was obtained in the concentration range of 0.06～0.6 mmol·L -1 (p<0 01). The detection limit is 9.2 nmol·L -1 .

关 键 词：磺胺二甲嘧啶钠 注射液差示脉冲极谱法 测定 

分 类 号：R978.2[医药卫生—药品]