CKD与非CKD患者冠状动脉钙化发生情况的比较研究  

The Comparison of Coronary Artery Calcification in CKD and Non - CKD Patients

作　　者：周继生 鲍宏达[2] 汪年松[2] 盛晓华[2] 崔勇平[2] 俞岗[2] 许涛[2] 

机构地区：[1]江西省星子县人民医院内科,星子332800 [2]上海交通大学附属第六人民医院肾内科,上海200233

出　　处：《中国中西医结合肾病杂志》2013年第7期586-589,共4页Chinese Journal of Integrated Traditional and Western Nephrology

基　　金：国家自然基金面上项目(No.81270824);上海市国际科技合作基金资助项目(No.11410708500);上海市科委引导类项目(No.114119a6100);上海市科委基金资助项目(No.11DZ1921904);上海市科委基础研究重大项目(No.11DJ1400101);上海市科委重大项目(No.11DZ1973103)

摘　　要：目的:比较CKD患者与非CKD患者的冠状动脉钙化情况。方法:选取473例曾在我院行冠脉CT检查的CKD及非CKD患者,通过收集其生化指标及冠脉CT检查结果,分析并比较两组患者冠状动脉钙化的发生情况。结果:CKD患者冠状动脉钙化的发生率为76.5%,且钙化累及分支更多,LAD、RCA多发。钙化组的尿素氮、血磷水平及钙磷乘积显著高于非钙化组,而GFR则显著低于非钙化组(P<0.01)。结论:CKD患者冠状动脉钙化发生率高,累及范围广,程度更重,且LAD、RCA钙化多发。钙化组的尿素氮、血磷水平及钙磷乘积显著高于非钙化组,而GFR则显著低于非钙化组。Objective：To compare the coronary artery calcification in CKD and non- CKD patients. Methods ：473 cases of CKD and non - CKD patients who has clone coronary CT examination in our hospital were selected. By collecting their biochemical tests indicators and coronary CT examination results, the occurrence and risk factors of coronary artery calcification in patients were ana- lyzed. Results ：The incidence of coronary artery calcification in CKD patients was 76.5%. The calcification in CKD patients involved more branch, and multiple in LAD and RCA. Urea nitrogen, phosphorus, and calcium r__ phosphate product in calcification group was significantly higher than that of non - calcified group, while GFR was lower than non - calcified group （ P 〈 0. 01 ）. Conclusion： The incidence of coronary artery calcification in CKD patients was higher than the non - CKD patients. Calcification group of urea nitro- gen, phosphorus and calcium - phosphorus product levels were significantly higher than non - calcified group, while GFR was signifi- candy lower than non - calcified group.

关 键 词：慢性肾脏病 钙磷代谢 冠状动脉钙化 

分 类 号：R692.3[医药卫生—泌尿科学] R541.4[医药卫生—外科学]