腹腔镜手术联合内异消癥汤治疗子宫内膜异位症不孕疗效观察  

Clinical Efficacy of Laparoscopic Operation Combined with Neiyi Xiaozheng Decoction on Endometriosis Associated with Infertility

作　　者：余韬[1] 冯云[1] 杨德红[1] 许鸿霞[1] 金凤丽[2] 

机构地区：[1]云南省第一人民医院,云南昆明650032 [2]云南中医学院,云南昆明650500

出　　处：《昆明医科大学学报》2013年第6期53-56,共4页Journal of Kunming Medical University

基　　金：云南省教育厅科学研究基金项目资助(2011J086)

摘　　要：目的探讨子宫内膜异位症(EM)不孕的治疗方法及腹腔镜手术联合内异消癥汤对其临床疗效.方法选择2011年6月至2011年12月,云南省第一人民医院收治的EM不孕患者60例,随机将其分为2组,第1组行腹腔镜手术后予期待治疗(对照组,n=30);第2组在第1组基础上加服内异消癥汤(观察组n=28).观察和比较治疗后各组患者临床疗效、妊娠率、血清癌抗原125、不良反应及复发率.结果观察组1 a妊娠率为67.86%,显著高于对照组(P<0.05);治疗后血清CA125水平为(12.71±10.08)U/mL,显著低于对照组(P<0.05);不良反应率与对照组相比差异无统计学意义(P>0.05).结论腹腔镜手术联合内异消癥汤可提高临床妊娠率,有效纠正血瘀状态,无明显不良反应,临床疗效确切.Objective This study was purposed to investigate the clinical efficacy of laparoscopic surgery combined with Neiyi Xiaozheng decoction on endometriosis （EM） associated with infertility. Methods Sixty patients with EM infertility in our hospital from June 2011 to December 2011 were selected and randomly divided into two groups. The control group received laparoscopic operation （n=30） and the observation group was treated with Neiyi Xiaozheng decoction on the basis of laparoscopie operation （n =28） . The clinical efficacy, pregnancy rate, serum cancer antigen 125 （CA125） , adverse reactions and relapse rate were observed and compared between the two groups. Results The pregnancy rate of observation group was 67.86% after one year which was significantly higher than that of control group （P 〈 0.05） . The serum CA125 level in the observation group was 12.71± 10.08 （U/ml） and it was significantly lower than that in the control group （P 〈 0.05） . But there was no obvious difference in adverse reaction rate between two groups. Conclusion Laparoscopic surgery combined with Neiyi Xiaozheng decoction could improve the clinical pregnancy rate and the blood stasis state. This method is effective for treating EM infertility without obvious adverse reaction.

关 键 词：子宫内膜异位症 不孕 腹腔镜 内异消癥汤 

分 类 号：R713.8[医药卫生—妇产科学]