新生儿VitK营养状况的研究  

Vitamin K Nutrition Status of Newborns

作　　者：张会丰[1] 阎华[1] 田秀巧[1] 安秀书 刘岩平[1] 范士英[1] Julia Harvey Martin J Shearer 陈连元[3] 

机构地区：[1]河北医科大学第二医院,050000 [2]伦敦圣托马斯医院维生素K研究室 [3]山西医科大学第一医院儿科

出　　处：《中国妇幼保健》2000年第8期498-499,502,共3页Maternal and Child Health Care of China

基　　金：河北省计生委科研基金

摘　　要：为了通过凝血酶原前体蛋白 (PIVKA- ) ,研究足月新生儿 Vit K的营养状况 ,对 96例健康的足月新生儿脐血 ,采用针对凝血酶原前体蛋白 (PIVKA- )的单克隆抗体酶联免疫吸附法 (EL ISA)进行了凝血酶原前体蛋白检测。结果 :96例新生儿脐血标本中 2 4例凝血酶原前体蛋白 (PIVKA- )阳性 ,检测值高于 0 .15 AU/ ml,阳性率是 2 5 %。范围 0 .170～ 8.86 0 AU/ ml。大约有 2 5 %的新生儿处于 Vit K缺乏状态。To study vitamin K nutrition status of newborns by means of determining protein induced by vitamin K absence peothrombin (II), PIVKA II, in 96 health newborns, PIVKA II of the cord blood samples were measured by ELISA of the monoclonal antibody. Result: in 24 of 96 samples of newborn blood, their concentrations of PIVKA II were higher than 0.15 AU/ml .The postive rates were 25%. The ranges were 0 170～8 860 AU/ml. There were about 25% of all newborns being vitamin K deficient status.

关 键 词：凝血酶原前体蛋白 新生儿 维生素K缺乏 ELISA 

分 类 号：R723.249[医药卫生—儿科]