改良的部分脾动脉栓塞治疗30例脾功能亢进临床效果研究  

Clinical efficacy studies on improved partial splenic embolization in the treatment of 30 cases with splenic function hypersplenism

作　　者：毛金忠 邵媛媛 李如刚 葛国洪 谭友文 吴翠松 

机构地区：[1]江苏省镇江市第三人民医院,江苏镇江212003

出　　处：《中国医药导报》2013年第23期49-51,共3页China Medical Herald

基　　金：江苏大学医学临床科技发展基金项目(编号JLY20120026)

摘　　要：目的评价改良的部分脾动脉栓塞治疗脾功能亢进的临床疗效及术后并发症。方法选择镇江市第三人民医院2010年1月～2012年6月住院治疗的脾功能亢进患者30例,行改良的部分脾动脉栓塞治疗,观察术后血常规、肝功能、门静脉内径、平均血流及并发症发生情况。结果 30例脾功能亢进患者栓塞术后化验外周血白细胞、血小板明显高于栓塞前,差异有统计学意义(P<0.05);肝功能术后1周较术前明显升高,差异均有统计学意义(P<0.05);患者术后1、2周和1、3、6个月门静脉压力、血管内径、每分血流量明显下降,与术前比较,差异有统计学意义(P<0.05);所有患者未发生消化道出血、明显腹痛、脾脓肿等严重并发症。结论改良的部分脾动脉栓塞是治疗脾功能亢进安全有效的方法,可明显提高患者的生活质量。Objective To evaluate the modified partial splenic artery embolization spleen hyperfunction clinical effica cy and postoperative complications.Methods 30 cases of hypersplenism patients in the Third People＇s Hospital of Zhenjiang City from January 2010 to June 2012 were selected,improved partial splenic artery embolization was used in the patients,the postoperative blood count,liver function,portal vein diameter,mean blood flow and complications were observed.Results WBC,PLT in 30 patients with hypersplenism after embolization were higher than those before the embolization,the differences were statistically significant（P 0.05）.The preoperative liver function after 1 week was higher than those before the operation,the differences were statistically significant（P 0.05）;portal venous pressure,blood vessel diameter,per minute blood flow 1,2 weeks,1,3,6 months after the operation were lower than those before the operation,the differences were statistically significant（P 0.05）.No gastrointestinal bleeding,obvious abdominal pain,splenic abscess was found.Conclusion The modified partial splenic embolization in treatment of hyper splenism is a safe and effective method,and can significantly improve the quality of life of patients.

关 键 词：脾脏功能亢进 脾动脉栓塞 并发症 

分 类 号：R657.6[医药卫生—外科学]