干预措施在Ⅰ类切口手术围术期抗菌药物预防应用中的效果评价  

Evaluation on effect of intervention on the perioperative antibiotics prophylactic in typeⅠincision operation

作　　者：李兵 张怡 李雪红[2] 任建安[3] 

机构地区：[1]广东省东莞康华医院临床药学室,广东东莞523080 [2]广东医学院药学系,广东东莞523080 [3]解放军南京军区南京总医院,江苏南京210002

出　　处：《中国医药导报》2013年第23期109-111,共3页China Medical Herald

基　　金：江苏省自然科学基金(编号BK2010017)

摘　　要：目的评价干预措施促进Ⅰ类切口手术围术期抗菌药物预防性合理应用的有效性和可行性。方法采用回顾性调查方法,抽取东莞康华医院普外科甲状腺手术、腹股沟疝修补术、浅表肿物切除术3种I类切口手术所有病例,干预前105例作为对照组,干预后139例作为干预组,调查分析抗菌药物预防性应用情况。结果与对照组相比,干预组抗菌药物预防使用率从100.00%降至35.25%(P<0.05),品种选择、给药时机等指标合理性显著提高(P<0.05),而术后切口感染率两组差异无统计学意义(P>0.05)。结论干预措施有效可行,能够提高围术期预防性应用抗菌药物的合理性。Objective To evaluate the effectiveness and feasibility of intervention on perioperative antibiotics prophy laxis in typeⅠincision operations.Methods A retrospective survey was conducted.Patients underwent 3 kinds of type Ⅰincision operations（thyroid surgery,inguinal hernia repair and superficial neoplasm resection） in General Surgery Department of Dongguan Kanghua Hospital were selected.105 cases before intervention were sampled as control group and 139 cases after intervention were sampled as intervention group.Investigation and analysis were performed in the perioperative antibiotics prophylaxis.Results Compared with control group,the intervention group antibiotics prophy laxis usage rate decreased from 100.00% to 35.25%（P 0.05）.Rationalities of drug selection and administration time in the intervention group significantly increased（P 0.05）.However,postoperative wound infection rate had no significant difference between the two groups（P 0.05）.Conclusion Implementation of effective and feasible interventions can promote the rational use of perioperative prophylactic antibiotics.

关 键 词：抗菌药物 围术期 干预 

分 类 号：R969.3[医药卫生—药理学]