藏药小叶莲的化学成分研究  

Studies on the Chemical Constituents of the Fruit of Sinopodophyllum emodi

作　　者：尚明英[1] 李军[1] 蔡少青[1] 李萍[2] 徐珞珊[2] 徐国钧[2] 

机构地区：[1]北京医科大学药学院生药学研究室,100083 [2]中国药科大学

出　　处：《中草药》2000年第8期569-571,共3页Chinese Traditional and Herbal Drugs

基　　金：国家"八.五"攻关项目

摘　　要：目的 :对藏药小叶莲的化学成分进行研究。方法 :采用硅胶色谱柱进行分离 ,通过物理、化学和光谱学方法鉴定各化合物的结构。结果 :分离并鉴定了 6个化合物 ,分别为去氧鬼臼毒素 (deoxypodophyllotoxin)、鬼臼毒素(podophyllotoxin)、4′-去甲去氧鬼臼毒素 (4′- demethdeoxypodophyllotoxin)、8-异戊烯基山柰酚 (8- prenylkeamf-erol)、柠檬酚 (citrusinol)和β-谷甾醇。结论 :各化合物均为首次从小叶莲中分得 ,其中 8- prenylkeamferol和The chemical constituents of the fruit of Sinopodophyllum emodi were isolated with silica gel chromatography and their structures identified by physical, chemical properties and spectral analysis As a result, six compounds were isolated and identified as deoxypodophyllotoxin, podophyllotoxin, 4′ demethyldeoxypodophyllotoxin, 8 prenylkeamferol, citrusinol, and β sitosterol All the compounds were isolated from Fructus Sino Podophylli for the first time 8 prenylkeamferol and citrusinol were found in Podophylloideae for the first time

关 键 词：小叶莲 鬼臼 毒素 桃儿七素 藏药 

分 类 号：R284.1[医药卫生—中药学]