当归油对大鼠离体子宫平滑肌收缩功能的影响  

Effect of the Oil of Angelica sinensis on the Contractile Function of Isolated Uterine Smooth Muscle of Mice

作　　者：闫升 乔国芳 刘志峰 刘珂 王嘉陵[2] 

机构地区：[1]山东省天然药物工程技术研究中心,烟台264000 [2]同济医科大学基础药理教研室

出　　处：《中草药》2000年第8期604-606,共3页Chinese Traditional and Herbal Drugs

摘　　要：当归油 (含藁本内酯 ligustilide>70 % ) ,用 1%吐温 - 80助溶 ,无论对正常未孕离体子宫还是对经缩宫素处理的离体子宫 ,都可剂量依赖性 (浴槽终浓度为 1mg/ 10 0 m L～ 32 mg/ 10 0 m L)地抑制子宫平滑肌的收缩功能 ,其性质与妇痛宁滴丸相似 ,但作用稍强 。The oil of Angelica sinensis (Oliv.) Diels (contains ligustilide > 70%), could markedly inhibit the contractile function of isolated uterine smooth muscle of mice in a concentration dependent manner (the utlimate bath concentration is 1 mg/100 mL～32 mg/100 mL) whether the test sample was isolated from normal or oxytocin treated mice. It proved that angelica oil had significant anticonvulsive effect in uterine smooth muscle of mice.

关 键 词：当归油 藁本内酯 子宫平滑肌收缩功能 大鼠 

分 类 号：R285.5[医药卫生—中药学]