气相色谱法测定克疣纳米乳中冰片和薄荷脑含量  

GC Determination of Synthetic Borneol and Menthol in Keyou Nanoemulsion

作　　者：樊静静[1] 袁玉霞[1] 尹香阁[1] 赵文龙[1] 贾永艳[1] 

机构地区：[1]河南中医学院,河南郑州450046

出　　处：《中国中医药信息杂志》2013年第8期52-54,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：郑州市科技攻关项目(0910SGYS33390-2)

摘　　要：目的建立克疣纳米乳中冰片、薄荷脑的气相色谱测定方法。方法 HP-5毛细管柱(30 m×320μm×0.25μm),氮气为载气,FID检测器,进样口温度为230℃。结果冰片、薄荷脑分离度良好,冰片在0.337～1.685μg范围内线性关系良好,r2=0.998 2,平均回收率为97.5%;薄荷脑在0.234～1.17μg范围内线性关系良好,r2=0.997 4,平均回收率为97.0%。结论该法简便、准确,可用于克疣纳米乳中冰片、薄荷脑的测定。Objective To establish the determination method synthetic borneol and menthol in Keyou nanoemulsion.Methods HP-5 quartz capillary column（30 m×320 μm×0.25 μm） was used with nitrogen as the carrier gas,and FID as the detector.The temperature of the entrance of the capillary vessel column was at 230 ℃.Results Synthetic borneol and menthol in Keyou nanoemulsion were separated well.The calibration curves of synthetic borneol was obtained with good linear relationship within the range of 0.337-1.685 μg（r 2=0.9982）,the average recovery was 97.5%.The calibration curves of menthol was also obtained with a good linear relationship within the range of 0.234-1.17 μg（r 2=0.997 4）,the average recovery was 97.0%.Conclusion The methord is simple and accurate.It can be used to control the quality of Keyou nanoemulsion.

关 键 词：克疣纳米乳 冰片 薄荷脑 气相色谱法 

分 类 号：R284.1[医药卫生—中药学]