经皮球囊肺动脉瓣成形术姑息治疗法洛四联症13例疗效评价  

Therapeutical evaluation of percutaneous balloon valvuloplasty for the treatment of pulmonary stenosis in children with tetralogy of Fallot

作　　者：周爱卿[1,2] 李奋[1,2] 高伟[1,2] 余志庆 

机构地区：[1]上海市儿科医学研究所,200092 [2]上海第二医科大学附属上海儿童医学中心

出　　处：《临床儿科杂志》2000年第4期195-197,共3页Journal of Clinical Pediatrics

基　　金：上海市卫生局基金编号93404

摘　　要：应用经皮球囊肺动脉瓣成形术(PBPV)姑息治疗法洛四联症13例,其中男8例,女5例;平均年龄(3.7±2.1)岁。SaO_2由术前平均75.5％±4.3％上升至术后91.3％±4.7％(P<0.001),肺动脉/漏斗部压差由(27±2.78)mmHg下降至(3.95±8.21)mmHg(P<0.01),肺动脉瓣环大小与术前相仿(13mm±3.5mm vs 14mm±2.7mm,P>0.05)。随访(1～2)年,病情稳定,Sa O_2大多维持在85％左右,均接受外科手术。结果表明,PBPV对一些病例作为替代外科姑息手术治疗法洛四联症是可行的,为最终外科根治创造良好条件。To evaluate the results of the percutaneous balloon pulmonary valvuloplasty (PBPV) for the treatment of pulmonary stenosis in children with tetralogy of Fallot, balloon dilatation of the pulmonary valve was performed in 13 children with tetralogy of Fallot at an average age of 3. 7±2.1 years (range 1 to 6 years). The ratio of balloon/pulmonary annulus diameter was 1. 3-1. 5 (mean 1. 4). The results showed that after balloon dilatation, the average of oxygen saturation (SaO2)increased from 75. 5%±4. 3% to 91. 3%±4. 7%(P<0. 001), the pressure gradient of pulmonary artery/infundibu-lum of right ventricle decreased from (27±2. 78)mmHg to(3. 95±8. 2)mmHg(P<0. 01), respectively. The size of valvular ring of pulmonary artery was similar before and after PBPV (13mm±3. 5 mm vs. 14mm±2. 7mm, P>0. 05). The patients were followed up 1-2 years and kept stable. The SaO2 in the most children remained about 85% and all patients later accepted successful surgery. It is concluded that PBPV is available clinically for the treatment of tetralogy of Fallot as a substitutive therapy palliatively. A good condition can be hence supplied for the radical cure surgically later on.

关 键 词：法洛四联症 经皮球囊肺动脉瓣成形术 PBPV 儿童 

分 类 号：R726.5[医药卫生—儿科]