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作 者:常宏[1] 李志玲[2] 邓少洁[1] 沈嘉茵[1] 程启飞 张丽
机构地区:[1]深圳市妇幼保健院药剂科,广东深圳518028 [2]复旦大学附属儿科医院 [3]江西省玉山县岩瑞中学,江西上饶334700 [4]江西省玉山县中医院外一科,江西上饶334700
出 处:《今日药学》2013年第7期442-444,451,共4页Pharmacy Today
基 金:广东省医院药学研究基金(奥赛康基金)资助项目(编号:20110A31)
摘 要:目的了解妊娠期妇女血清微量及宏量元素缺乏情况,并探讨预防措施。方法选择在本院进行孕期产检并分娩的孕妇共9 698例进行分组分析,800名正常妇女为对照组。采用原子吸收光谱仪检测钙(Ca)、铜(Cu)、铁(Fe)、钾(K)、镁(Mg)、钠(Na)、铅(Pb)、锌(Zn)8种元素,并比较2组各微量元素的缺乏率。结果孕妇组的铁(Fe)、钙(Ga)含量明显低于对照组,有显著性差异(P<0.05);同时铁元素、钙元素缺乏的发生率随孕妇年龄的增大而明显上升(P<0.05);钙元素缺乏的发生率随孕妇孕周的增大而明显上升(P<0.05);孕妇组的铅含量明显高于对照组(P<0.05)。结论女性妊娠期应定期进行微量元素及宏量元素的监测,根据不同孕周、不同年龄及时进行调整。Objective To study the situation of the serum trace elements and macro elements deficiency in pregnant women, and to explore preventive measures. Methods A total of 9 698 women who had prenatal examinations and a labor delivery in the hospital were selected as experimental group, and 800 women without pregnancy were selected as control group. 8 elements in the serum, such as calcium ( Ca), copper ( Cu), iron ( Fe ), potassium ( K), magnesium (Mg) ,sodium(Na), plumbum (Pb), zinc (Zn) detected by atomic absorption spectrometer, were compared in the 2 groups. Results With increasing gestational age, the absent ratio of iron, calcium were significantly higher than those in control group(P 〈 0.05 ), in which the calcium and iron deficiency were correlated with the pregnancy gestation. The plumbum in pregnant group were significantly higher than those of the control group. Conclusion Women during pregnancy should regularly monitor the microelements and macro elements, and to adjust in time depending on gestational week, age and so on.
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