某院485例Ⅰ类切口手术围术期预防性使用抗菌药物调查分析  

Investigation and Analysis of Perioperative Application of Antibacterial Drug in 485 Cases of TypeⅠIncision Operation

作　　者：黎行山[1] 李咏梅[1] 杨晓[1] 陈燕红[1] 

机构地区：[1]广州医科大学第五附属医院药剂科,广东广州510700

出　　处：《今日药学》2013年第7期445-448,共4页Pharmacy Today

摘　　要：目的调查本院Ⅰ类切口手术围术期预防性应用抗菌药物情况,并评价其合理性。方法抽取本院2011-10～2012-09出院的485份Ⅰ类切口手术病历进行调查及分析。结果本院Ⅰ类切口手术围术期预防使用率达85.57%,预防用抗菌药物主要以第一代头孢菌素为主,使用最多的是五水头孢唑啉392例,占77.78%,其次是头孢硫脒21例,占4.17%,394例患者于术前0.5～2 h给药,176例术后抗菌药物预防使用时间大于48 h。结论本院Ⅰ类切口手术围术期抗菌药物合理应用现状与卫生部的要求仍有较大差距,需进一步加强抗菌药物合理应用的管理,以提高本院合理用药水平。Objective To investigate the perioperative utilization of prophylactic antibiotics in patients undergoing type I incision operations in the hospital and to evaluate its rationality. Methods A total of 485 cases medical records of type I incision operation during Oct 2011 to Sep 2012 were analyzed. Results The rate of perioperative application of prophylactic antibiotics for patients undergoing type I incision operations was 85. 57%. Antibiotics for prophylactic application were mainly first generation cephalosporin. The most commonly used antibiotics was 392 cefazolin sodium, which accounted for 77.78%, followed by 21 cefathiamidine 4.17%. Antibiotics were used in 394 cases within 0.5 - 2 h before operation, and 176 cases used antibiotics more than 48 h after the operation. Conclusion There is still a certain gap between the status quo of antimicrobial application of type I incisions operations in the hospital and the request of the Ministry of Health for the rational application of the antimicrobial agents, therefore the management for the rational application of antimicrobial agents should be strengthened to improve hospital rational drug application level.

关 键 词：Ⅰ类切口手术 抗菌药物 围手术期 合理用药 

分 类 号：R97[医药卫生—药品]