小剂量肾上腺素抢救哮喘持续状态的疗效观察  

Observation on therapeutic effects of small dose epinephrine in rescue of status asthmaticus

作　　者：王琪[1] 金志鹏[1] 苏军[1] 马洁[1] 

机构地区：[1]郑州市儿童医院儿童重症监护室(PICU),450053

出　　处：《中国实用医药》2013年第21期10-11,共2页China Practical Medicine

摘　　要：目的探讨小剂量肾上腺素治疗哮喘持续状态的临床应用。方法 2010年1月至2012年12月在本科PICU收治哮喘持续状态的患儿69例,根据治疗不同,计为观察组(持续小剂量肾上腺素泵入)38例,对照组(氨茶碱)31例。对比两组患儿治疗前后疗效及血气分析指标。结果两组患儿疗效差异有显著统计学意义(P<0.01);血气分析比较,两组治疗后的动脉血氧分压(PaO2)差异有统计学意义(P<0.01);对于PaO2治疗前后变化,两组间差异有统计学意义(P<0.01)。结论小剂量肾上腺素持续泵入对有效缓解哮喘持续状态具有一定临床意义。Objective To explore the clinical application of small dose epinephrine in continuous pump for children with status asthmaticus. Methods 69 cases of children with status asthmaticus to pediatric intensive care unit in our hospital from January 2010 to December 2012 were divided into the observed group（continuous pump small dose epinephrine） and the control group（aminophylline）. Compared clinical efficacy and indicators of blood gas analysis before and after treatment. Results Difference of clinical efficacy between the two groups was significant（ P 0.01）.After treatment, Values of arterial partial pressure of oxygen（PaO 2 ）of the two groups was obviously different（ P 0.01）.Compared with the control group, change of PaO 2 in the observed group was significant before and after treatment（ P 0.01）. Conclusion Application of small dose epinephrine in continuous pump may be has certain significance for effective relief of status asthmaticus.

关 键 词：肾上腺素 小剂量 哮喘 哮喘持续状态 儿科学 

分 类 号：R725.6[医药卫生—儿科]