皮肤伸展术后生物力学和组织学的实验研究  

BIOMECHANICAL AND HISTOMORPHOLOGICAL CHANGES IN STRETCHED PIG SKIN

作　　者：周黎安[1] 李谆[1] 郭树忠[2] 艾玉峰[2] 查元坤[1] 鲁开化[2] 高岚[1] 

机构地区：[1]解放军451医院整形外科,西安710054 [2]第四军医大学西京医院整形外科中心,西安710032

出　　处：《中国美容医学》2000年第4期244-246,250,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的 :观察皮肤伸展作用后生物力学特性和组织学的改变。方法 :取 4只体重 2 0 kg左右的猪为实验动物 ,采用自身对照方式进行 ,对伸展作用侧及对照侧皮肤标本分别进行拉伸断裂强度、拉伸断裂伸长百分率、皮肤本构关系等生物力学指标的测定及组织学的检查。结果 :伸展皮肤的粘弹性下降。组织学观察可见伸展后表皮细胞层次增多 ,真皮层稍变薄。结论 :皮肤伸展作用后 ,其生物力学性质及组织学均有明显变化。临床上可采用皮肤伸展术 ,以缩短疗程 。Objective:The study was designed to observe the biomechanical and histomorphological changes in stretched pig skin Methods:On 4 pigs stretched skin was compared with non stretched control skin from the opposite side of the animal,using a paired t test The biomechanical and histomorphological properties were determined in stretched and non stretched control skin By using tensometer,the sin was evaluated for stress strain and parameters of strength Result:The biomechanical properties of the stretched skin were different from the control skin Histomorphological examination revealed that the epidermis layer increase There was thinning of dermis,the dermal collagen bundles were thicker than those of controle Conclusion:We concluded that the biomechanical properties and histomorphological changes were different from that of the unstretched skin It was shown that the skin stretching technique might be accepted in the practice

关 键 词：皮肤伸展术 生物力学特性 组织学检查 

分 类 号：R622[医药卫生—整形外科] R318.01[医药卫生—外科学]