生殖激素与男性不育症患者精子形态的相关性分析  

Correlation analysis of reproductive hormones and sperm morphology in infertile men

作　　者：陈创奇[1] 史哲[1] 黄志承[1] 董云巧[1] 黄郁强[1] 汪李虎[1] 

机构地区：[1]广东省妇幼保健院生殖健康与不孕症科,广州510010

出　　处：《中国性科学》2013年第7期71-74,共4页Chinese Journal of Human Sexuality

摘　　要：目的:研究生殖激素与男性不育症患者精子形态,探讨两者的相关性。方法:对象为2008年8月至2012年我院600例男性不育症患者,根据正常形态精子所占比例大小分为三个组,每组200例。结果:三组患者血清游离睾酮(free testosteron,FT)水平与生物活性睾酮(bioavailable testosterone,Bio-T)水平,均只有在第1组与第3组之间存在统计学的差异。另外,血清FT、Bio-T水平与正常形态精子百分率之间均存在正相关(P<0.05)。结论:男性不育症患者血清FT和Bio-T水平越高,则正常形态精子百分率越高,提示生殖激素与男性不育症患者精子形态存在着相关性。Objectives： To explore reproductive hormones and sperm morphology of infertile men and to explore the correla- tion between them. Methods. From August 2008 to August 2012, 600 infertile men aged from 25 to 45 were included in our study. Based on the results of sperm morphology analyses, the 600 infertile men were randomly divided into three groups, 200 in each group. Results： The levels of serum free testosterone and bioactive testosterone were the only differences in statistics between the first group and the third group. The levels of serum FT and BioT were positively correlated with the percentage of morphologically nor- real sperm （P 〈 0. 05）. Conclusion： The higher the levels of serum FT and BioT are, the higher the percentage of morphologically nor- mal sperm is, which suggests positive correlation exists between reproductive hormones and sperm morphology in infertile men.

关 键 词：男性不育症 精子形态学分析 生殖激素 游离睾酮 生物活性睾酮 

分 类 号：R698.2[医药卫生—泌尿科学]