乙肝病毒载量对妊娠期糖尿病的妊娠结局的影响  

Study on the influence of hepatitis B virus load on pregnancy outcome of gestational diabetes mellitus

作　　者：翟红卫[1] 焦瑞芬[2] 张瑞萍[1] 吕克蔺[1] 张燕[1] 杨翠丽[1] 王力英[1] 史昭[1] 刘丽芬 

机构地区：[1]石家庄市第六医院妇产科(石家庄市妇幼保健院),河北省石家庄050051 [2]石家庄市妇产医院产科 [3]石家庄市优抚医院产科

出　　处：《中国基层医药》2013年第16期2429-2431,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 通过观察某院收治的妊娠期糖尿病分娩孕妇临床治疗资料,探讨分析乙肝病毒（HBV）携带载量对妊娠期糖尿病（GDM）的发生率及对妊娠结局的影响.方法 对13 565例住院分娩孕妇分为乙型肝炎病毒携带病毒载量阳性组（A组）、病毒载量阴性组（B组）及非乙型肝炎病毒携带组（C组）三组,均进行肝功能、HBV血清学、血糖等方面的检测,并记录相关妊娠结局情况,对比分析三组GDM发生率、产妇糖尿病的预后情况以及对胎儿的影响情况.结果 A组中GDM的发生率为3.80％,B组中GDM的发生率为4.03％,C组中GDM的发生率为2.36％,三组13 565例孕妇中不同乙肝病毒载量之间GDM的发生率、产妇糖尿病的预后以及对胎儿的影响情况等差异无统计学意义（P＞0.05）.结论 乙肝病毒（HBV）携带载量的妊娠期糖尿病（GDM）的发生率对比差异无统计学意义,且病毒载量的水平不改变糖尿病的预后以及胎儿差异情况,妊娠结局未受影响,但是乙肝病毒携带者GDM的发生率对比非乙肝病毒携带者孕妇明显高.Objective Through observing the clinical data of patients with gestational diabetes mellitus （GDM）,to,analyze the influence of hepatitis B virus （HBV） viral load on pregnancy outcome of GDM patients.Methods 13565 cases of pregnant women were divided into HBV carry virus positive group（group A）,virus negative group（group B） and the non HBV carry group（C group）.The liver function,HBV serological test,blood sugar,etc were detected in all three groups,and related pregnancy outcome was recorded.The incidence rate of GDM,prognosis of maternal diabetes and its influence to the fetus were compared.Results The incidence rate of GDM in A,B,C group was 3.80％,4.03％,2.36％,respectively.The incidence rate of GDM in different HBV viral load pregnant women,prognosis of maternal diabetes and the influence to the fetus between groups had,no statistically significant differences （P ＞0.05）.Conclusion The incidence rate of GDM in different HBV carrying capacity patients had no significant difference,and viral load level did not change the prognosis of diabetes and fetal variance,the pregnancy outcome was not affected,but the incidence rate of GDM in HBV carriers was higher than non HBV carriers.

关 键 词：妊娠期糖尿病 乙型肝炎病毒 病毒载量 妊娠结局 影响分析 

分 类 号：R714.256[医药卫生—妇产科学]