近红外光谱法鉴别怀地黄药材道地性的研究  

Identification of Rehmanniae Radix genuineness regional drugs by near-infrared spectroscopy

作　　者：司南[1] 杨柳 王宏洁[1] 杨健[1] 李鹏跃[1] 赵海誉[1] 边宝林[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]皆能(亚洲)有限公司,北京100044

出　　处：《现代药物与临床》2013年第4期542-546,共5页Drugs & Clinic

基　　金：中国中医科学院自主选题项目

摘　　要：目的运用近红外光谱法区分道地与非道地生地黄药材。方法大量收集道地产地及其他产地的生地黄药材,对药材进行处理后,运用Foss XDS Smart ProbeTM近红外原料分析仪;PbS-硅;数据分析波长:780～2200nm;每个样品扫描4次。结果得到600余张近红外光谱,采用残差分析方法进行分析,阈值用ID(≤0.84)和Qual(≤0.79)两个量进行限定,能够较好区分样品中道地与非道地产区来源的样品。结论利用近红外光谱技术能够实现对地黄药材道地性的鉴别。Objective To identify the Rehmanniae Radix from genuineness or non genuineness habitats by using near-infrared spectroscopy （NIR）. Methods The samples were collected widely from the genuine regions and other habitats of Rehmanniae Radix. All the samples were analyzed by Foss XDS Smart ProbeTM; Pbs-Si; and data analysis wavelengths were 780—2 200 nm. Each sample was rescanned for four times. Results Six hundred NIRS spectra were obtained, and the NIR data were analyzed by residual analysis. The threshold values were limited by ID≤0.84 and Qual ≤0.79. Conclusion NIR is an accurate, fast, and simple method for the distinguishing of Rehmanniae Radix from genuine regions or not.

关 键 词：地黄 道地药材 近红外光谱 

分 类 号：R286.02[医药卫生—中药学]