中西医结合治疗狼疮性肾炎的临床研究文献分析  

Analysis of The Clinical Research Literature on The Treatment of Lupus Nephritis with Integrated Traditional Chinese Medicine and West Medicine

作　　者：汤丽萍[1] 彭晓青[1] 

机构地区：[1]广州市第一人民医院药剂科,广州510180

出　　处：《中国医院用药评价与分析》2013年第7期613-615,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:对近13年来发表的中西医结合治疗狼疮性肾炎的临床研究文献进行归纳、总结及分析,为临床合理用药提供依据。方法:通过计算机检索相关数据库获取文献(检索时间为2000—2012年),对每篇纳入文献的样本量、方药组成、疗效评价等指标进行分析。结果:共有57篇文献纳入分析,方剂中出现频数较高的有黄芪、白花蛇舌草、生地、丹皮、丹参等;所有文献均无样本量估算及随机方法描述;文献的疗效判定标准不一。结论:中西医结合治疗狼疮性肾炎的临床研究文献质量一般,研究水平有待提高。OBJECTIVE：To summarize and analyze the clinical research literatures on the treatment of lupus nephritis with integrated traditional Chinese medicine and west medicine published in recent 13 years so as to provide reference for clinical rational use of drugs. METHODS： The literatures during the period 2000-2012 were retrieved from the relevant database by computer. Each of the included literatures was analyzed with regard to sample size, the compositions in prescriptions and the indicators of therapeutic efficacy. RESULTS： A total of 57 literatures were included. The compositions seen frequently in prescriptions included astragalus, spreading hedyotis herb, rehmannia dride rhizome, cortex moutan and salvia miltiorrhiza etc. Neither estimation of sample size nor description of random methods was noted in the literatures. The criteria for evaluation of the therapeutic efficacy in the literatures were different from each other. CONCLUSION： The quality of the literature of clinical research on the treatment of lupus nephritis with integrated traditional Chinese medicine and west medicine is far from perfect thus the research level remains to be improved.

关 键 词：狼疮性肾炎 中西医结合 临床研究 文献 

分 类 号：R93[医药卫生—生药学]