天麻醒脑胶囊联合氟桂利嗪治疗血管神经性头痛的临床研究  

Clinical Research in the Treatment of Angioneurotic Headache with Tianma Xingnao Capsules and Flunarizine

作　　者：潘金山 乔钦增[2] 张永红[2] 

机构地区：[1]河北省邢台县白岸医院,河北邢台054000 [2]河北省民政总医院,河北邢台054000

出　　处：《世界中西医结合杂志》2013年第7期693-695,共3页World Journal of Integrated Traditional and Western Medicine

基　　金：河北省邢台市科技计划项目(No.2012ZC054)

摘　　要：目的观察天麻醒脑胶囊联合氟桂利嗪治疗血管神经性头痛的疗效。方法将2010年1月～2012年6月我院内科门诊血管神经性头痛患者90例,按随机抽样法分为治疗组30例、对照Ⅰ组30例和对照Ⅱ组30例。治疗组给予天麻醒脑胶囊联合氟桂利嗪;对照Ⅰ组给予天麻醒脑胶囊,对照Ⅱ组给予氟桂利嗪。两组治疗时间均为12周,停药后随访4周。观察两组临床疗效及不良反应发生率。结果治疗组头痛疗效指标优于两对照组(P<0.05)。治疗组总有效率为93.33%,对照Ⅰ组总有效率为80.00%,对照Ⅱ组总有效率为83.33%。治疗组总有效率明显优于两对照组(P<0.05),治疗组不良反应发生率低。结论天麻醒脑胶囊联合氟桂利嗪治疗血管神经性头痛的头痛频率、头痛持续时间及头痛程度明显改善,不良反应发生率低,值得临床推广应用。Objective To observe the efficacy on angioneurotic headache treated with Tianma Xing nao Capsules and Flunarizine. Methods Ninety cases of angioneurotic headache were collected from the In ternal Medicine Department of the Hospital from January 2010 to June 2012 and were divided into a treatment group （30 cases） , a control Ⅰ group（30 cases） and a control Ⅱ group （30 cases） according to randomization method. In the treatment group ,Tianma Xingnao Capsules and Flunarizine were administered in combination. In the control I group,Tianma Xingnao Capsules were prescribed. In the control Ⅱ group, Flunarizine was prescribed. The treatment was 12 weeks for all the groups and the follow - up visit was 4 weeks after medici nal discontinuity. The clinical efficacy and the incidence of adverse reactions were observed in the groups. Results The efficacy index of headache in the treatment group was superior to that in the two control groups （P 〈0.05）. The total effective rate was 93.33% in the treatment group,was 80.00% in the control Ⅰ group and was 83.33% in the control Ⅱ group. The total effective rate in the treatment group was better ap parently than that in either of the control groups（P 〈 O. 05 ）. The incidence of adverse reactions in the treat ment was low. Conclusion Tianma Xingnao Capsules and Flunarizine apparently reduce the onset frequen cy, persistent duration and severity of angioneurotic headache, as well as the incidence of adverse reactions and deserve to be promoted in clinical practice.

关 键 词：天麻醒脑胶囊 氟桂利嗪 血管神经性头痛 疗效观察 

分 类 号：R285.6[医药卫生—中药学] R441.1[医药卫生—中医学]