蒙药萨丽嘎日迪+协日嘎-4味汤对早期糖尿病肾病的疗效观察  

Curative Effect Observation on Mongolian SA Dew de Di + Xieri GA-4 Soup for Early Diabetic Nnephropathy

作　　者：刘萨仁[1] 张春花[1] 吴国华[1] 

机构地区：[1]内蒙古民族大学附属医院,内蒙古通辽028000

出　　处：《中国实验方剂学杂志》2013年第16期293-296,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：内蒙古自然科学基金项目(2011MS1165)

摘　　要：目的:探讨蒙药萨丽嘎日迪+协日嘎-4味汤治疗早期糖尿病肾病(热性希京病)的有效性和安全性。方法:80例患者随机按数字法分成治疗组和对照组各40例。治疗组在常规西药降血糖治疗基础上加用蒙药萨丽嘎日迪+协日嘎-4味汤治疗;对照组常规用西药降血糖治疗,疗程均为8周。观察两组治疗前后蒙医症候、24 h尿微量白蛋白变化。结果:治疗组临床总有效率达90%优于对照组的77.5%(P<0.05);治疗后治疗组24 h尿微量白蛋白排泄率(49.45±16.86)μg.min-1低于对照组的(96.52±22.56)μg.min-1(P<0.01);治疗组在蒙医单项症状小便混浊、尿频量多、腰膝酸软及倦怠无力的改善方面优于对照组(P<0.05);两组患者在治疗期间未发生任何不良反应。结论:蒙药萨丽嘎日迪+协日嘎-4味汤治疗早期糖尿病肾病安全有效,值得临床使用和进一步研究。Objective： To study the efficacy and safety of Mongolian SA dew de Di ＋ Xieri GA-4 soup in the treatment of early diabetic nephropathy （ Rexingxijin disease）. Method： According to digital method, 80 patients with divided into two groups randomly treatment group and control group, 40 cases each. Treatment group on the basis of conventional treatment with western medicine fall blood sugar added with Mongolian SA dew de Di ＋ Xieri GA-4 soup treatment. Control group with western medicine fall blood sugar, a course of 8 weeks. Observed two groups＇ Mongolian medicine symptoms, 24 h urine trace albumin before and after the treatment. Result： The clinical total effective rate of treatment group was 90%, was better than that of control group 77.5% （P 〈 0.05 ） ; After treatment, 24 h urine trace albumin excretion rate （49.45 ± 16.86） μg·min^-1 of treatment group was lower than control group （96.52 ± 22.56） μg·min^-1 （P 〈 0.01 ）. Treatment group in Mongolian medicine single symptom urine was cloudy, frequency quantity more fatigued, lumbar debility improvement better than that in control group （ P 〈 0. 05 ）. Two groups during treatment without any adverse reaction occurred. Conclusion ： Mongolian SA dew de Di ＋ Xieri GA-4 soup in the treatment of early diabetic nephropathy is safe and effective, worthy of clinical use and further study.

关 键 词：蒙医药治疗 早期糖尿病肾病 24 h尿微量白蛋白 

分 类 号：R287[医药卫生—中药学]