血必净注射液对严重胸部外伤患者应急及免疫状态影响的研究  

Xuebijing injection in patients with severe chest trauma emergency and the effects on immune status

作　　者：姜伟青[1] 王建伟[1] 彭保国[1] 姜协[1] 赵杰[1] 鲁海婷[1] 杨晓峰[1] 杨波[1] 吕强[1] 

机构地区：[1]常州市武进中医医院外科(南京中医药大学附属武进医院),江苏常州213151

出　　处：《中国急救医学》2013年第8期695-697,共3页Chinese Journal of Critical Care Medicine

基　　金：常州科技项目（CJ20122002）

摘　　要：目的探讨血必净注射液对严重胸部外伤患者应急及免疫状态的影响。方法符合诊断标准的胸部外伤患者60例，随机分为试验组和对照组，两组分别在第1、3、7天抽血查C-反应蛋白（CRP）、免疫球蛋白（IgA、IgG、IgM）、补体（c3、C4）及周围血白细胞（WBC）。结果比较两组第1天的检查结果，其免疫球蛋白、补体均见不同程度的下降，CRP和WBC升高，但两组比较差异无统计学意义（P〉0．05）；第3天两组的免疫球蛋白和补体开始回升，CRP和WBC开始下降，第7天大部分指标已接近正常，两组比较差异有统计学意义（P〈0．05）。结论血必净注射液具有提高胸部外伤患者的免疫功能、减轻炎性反应、促使机体尽早康复的作用。Objective To observe the effect of Xuebijing injection on the emergency and immune status in patients with severe chest trauma. Methods 60 patients diagnosed as chest trauma were randomly divided into experimental group and control group. Blood was drawn at 1, 3, 7 day to check blood CRP, C3, C4, IgA, IgG, IgM and WBC. Results At day 1, immunoglobulins and complements were relative low; CRP and WBC were relative high; but they are not significantly different between the two groups （P 〉 O. 05）. From day 3 immunoglobulins and complements began to increase; CRP and WBC began to decrease. At day 7 the data between two groups were statistically difference. Conclusion Xuebijing injection improves the immune function in patients with chest trauma, reduces inflammatory reaction, and improves prognosis.

关 键 词：胸部外伤 免疫球蛋白 血必净 补体 急性呼吸窘迫综合征(ARDS) 全身炎症反应综合征(SIRS) C-反应蛋白(CRP) 

分 类 号：R259.9[医药卫生—中西医结合]