消炎止痒洗剂中药材的提取方法研究  

Study on Extraction Technology of Medicinal Material from Anti-inflammation and Antipruritic Lotion

作　　者：莫国栋 杨瑾 梅全喜[2] 翁舜龙 梁丽嫦 

机构地区：[1]中山市第二人民医院,广东中山528447 [2]广州中医药大学附属中山医院,广东中山528447

出　　处：《中国药房》2013年第31期2920-2922,共3页China Pharmacy

基　　金：中山市科技计划(医疗卫生)资助项目(No.20122A167)

摘　　要：目的:探讨消炎止痒洗剂中药材的提取方法。方法:采用高效液相色谱法测定黄芩苷、盐酸小檗碱含量,并以此为指标,比较水提醇沉、醇提水沉、醇提水沉结合水提醇沉(不调pH值)、醇提水沉结合水提醇沉(调pH值)4种方法的提取效果。结果:水提醇沉方法下黄芩苷含量最高,醇提水沉结合水提醇沉(不调pH值)方法下盐酸小檗碱含量最高,但醇提水沉方法下二者的含量相当且处于中间水平,故选择醇提水沉法提取。结论:所选工艺稳定、可行,可用于消炎止痒洗剂中药材的提取。OBJECTIVE： To discuss the extraction method of Anti-inflammation and antipruritic lotion. METHODS：The con- tents of baicalin and berberine hydrochloride were determined by HPLC and used as index, the extraction effects of water extrac- tion and alcohol precipitation, alcohol extraction and water precipitation, combination of two methods （no change of pH value）, combination of two methods （adjusting pH value） were compared. RESULTS： By using water extraction and alcohol precipitation, the content of baicalin was the highest; by using alcohol extraction and water precipitation combined with water extraction and alco- hol precipitation（No change of pH value）, the content of berberine hydrochloride was the highest; by using alcohol extraction and water precipitation, the contents of above 2 materials were in the medium level. The alcohol extraction and water precipitation was the optimal method. CONCLUSIONS： The process is stable and feasible, and can be used for the extraction of Anti-inflammation and antipruritic lotion.

关 键 词：消炎止痒洗剂 提取方法 黄芩苷 盐酸小檗碱 

分 类 号：R284.2[医药卫生—中药学] R283[医药卫生—中医学]