献血者感染梅毒影响因素的病例对照研究  

Case control study of influencing factors on blood donors infected with syphilis

作　　者：李书平[1] 罗利平[2] 何毅[1] 万浬科[1] 张杰[1] 覃沙[1] 张蓝江[1] 严渝文[2] 

机构地区：[1]成都市血液中心,四川成都610041 [2]成都医学院

出　　处：《现代预防医学》2013年第16期2979-2981,2986,共4页Modern Preventive Medicine

摘　　要：目的研究献血者感染梅毒的危险因素及献血者筛选的相关问题。方法对215名TP检测为阳性的献血者及430名阴性献血者进行病例对照研究,应用多因素条件Logistic回归模型分析与感染梅毒有关的因素,并对危险因素的人群归因危险度(PAR)进行估计。结果筛选出与感染梅毒有关的因素有:多个性伴侣、不用安全套、共用剃刀、打耳洞、纹身,其危险度(OR值)分别为:2.7599,4.9542,1.4453,2.0893,6.4357,人群归因危险度分别为:21.21%,57.32%,21.93%,18.34%,2.32%,5项危险因素总的人群归因危险度为77.61%。结论献血者献血前筛查的工作有待进一步完善,梅毒的经血传播途径不容忽视。OBJECTIVE To evaluate the risk factors of syphilis among volunteer blood donors. METHODS 215 blood donors with positive ELISA results for TP were allocated into case group, and 430 blood donors tested negative into control group. A standardized questionnaire was used to collect data concerning demographic aspect and potential risk factors. The data of case and control groups were compared using Logistic regression to calculate crude and adjusted odds ratios, and 95% confidence intervals for risk factors. RESULTS According to the multiple condition Logistic regression model, multiple sexual partner, sex without condoms, razor sharing, ear piercing and tattooing increased the risk of syphilis infection, and the OR value for these items was 2.759 9, 4.954 2, 1.445 3, 2.089 3, and 6.435 7, respectively, and PAR for each of them was 21.21%, 57.32%, 21.93%, 18.34% and 2.32%, respectively, and the total PAR was 77.61%. CONCLUSION The screening work before blood donation should be further improved and the transmission of syphilis through blood should be paid more attention to.

关 键 词：梅毒 献血前筛查 多个性伴侣 不用安全套 共用剃刀 人群归因危险度 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]