内蒙古自治区育龄期妇女接种破伤风类毒素免疫效果评价  

Evaluation of tetanus toxoid immunization of childbearing age women in Inner Mongolia Autonomous Region

作　　者：闫绍宏 魏永刚 武贵森 夏伟[3] 金仁杰 陈永生 白吉日根 

机构地区：[1]内蒙古疾病预防控制中心,内蒙古呼和浩特010020 [2]北京天坛生物制品股份有限公司 [3]中国疾病预防控制中心 [4]兴安盟疾病预防控制中心 [5]兴安盟科右中旗预防控制中心

出　　处：《现代预防医学》2013年第16期3015-3016,3019,共3页Modern Preventive Medicine

摘　　要：目的评价内蒙古自治区农村、牧区育龄期妇女开展破伤风类毒素(TT)接种的效果。方法在开展破伤风类毒素接种的突泉县和未开展接种的扎赉特旗分别采用东西南北中5个方位抽取10个乡级单位,用间接血凝方法检测487名18～35岁育龄期妇女破伤风抗毒素(TAT)抗体水平。结果开展TT接种的突泉县育龄期妇女达到破伤风保护水平43.1%(﹥0.01IU/ml),TAT几何平均滴度为0.034IU/ml;而未开展TT接种的扎赉特旗育龄期妇女破伤风保护率为8.33%,TAT几何平均滴度为0.0055IU/ml。结论育龄期妇女TT接种是消除新生儿破伤风的策略之一,做好新生儿破伤风高危地区育龄期妇女TT接种,消除新生儿破伤风效果显著,应加强对18～35岁低年龄组育龄期妇女的TT接种。OBJECTIVE To evaluate the effect of tetanus toxoid immunization of childbearing age women in rural and pastur- ing areas of Inner Mongolia Autonomous Region. METHODS 10 counties were collected from the east, west, north, south and middle directions in Tuquan County which developed the tetanus toxoid immunization as well as the Zalaiteqi which did not develop the immunization respectively. From these 10 counties, 487 childbearing age women were aged 18-35 collected randomly and their antibody level of serum tetanus antitoxin （TAT） were detected by indirect blood coagulation and general situation investigation on. RESULTS In Tuquan County, the protection rate reached 43.1% （ 〉 0.01 IU/ml） and the TAT geometry average titer was 0.034 IU/ml. In Zalaiteqi, the protection rate was 8.33% and the TAT geometry average titer was 0.005 5 IU/ml. CONCLUSION The tetanus toxoid immunization of childbearing age women is one of the strategies to elimi- nate the neonatal tetanus, so we should strengthen the tetanus toxoid immunization of childbearing age women from 18 to 35 years old.

关 键 词：新生儿破伤风 育龄期妇女 破伤风类毒素 血清学效果 

分 类 号：R517.3[医药卫生—内科学]