肥胖儿童高血压和心脏损害发生率的临床研究  

The incidence of obese children with hypertension and heart damage

作　　者：李娜[1] 穆亚平[1] 刘立旻[2] 赵方[1] 马洪刚[1] 王岩[1] 李玢[1] 关丽君[1] 李书琴[3] 辛颖[3] 

机构地区：[1]沈阳市儿童医院,110032 [2]中国医科大学,沈阳110001 [3]中国医科大学附属盛京医院,沈阳110004

出　　处：《中国小儿急救医学》2013年第4期395-397,共3页Chinese Pediatric Emergency Medicine

摘　　要：目的探讨肥胖儿童高血压和心脏损害情况。方法选择2008年7月至2010年10月沈阳市儿童医院儿保门诊就诊的单纯性肥胖儿童516例为肥胖组，100例体检体重正常儿童为对照组。所有入组儿童均常规测量血压、心脏超声检查。结果肥胖组收缩压、舒张压均高于对照组（P〈0．05），肥胖组高血压检出率为3．88％（20／516）。所有儿童左心收缩功能均正常，肥胖组左室壁增厚22例，平均厚度为（0．93±0．07）cm，与对照组比较差异无统计学意义（P〉0．05）；肥胖合并高血压组儿童左室壁增厚19例，肥胖合并血压正常组儿童左室壁增厚3例，两组比较差异有统计学意义（P〈0．05）；肥胖组心包外脂肪增厚268例，平均厚度（3．372±0．098）mm，与对照组比较差异有统计学意义（P〈0．001）。结论肥胖儿童高血压发生风险高于非肥胖儿童；肥胖儿童心包外脂肪增厚明显高于正常体黾儿童，肥胖合并高血压儿童左室壁增厚高于血压正常儿童。Objective To explore the occurrence of hypertension and heart damage of obese chil- dren. Methods We selected 516 cases of obese children as obese group,hospitalized from Jul 2008 to Oct 2010 in Shenyang Children＇s Hospital. We also selected 100 cases of normal weight children as control group at the same time. All enrolled children were measured blood pressure, cardiac ultrasound routinely. Results The systolic blood pressure and diastolic blood pressure of obese group were higher than those of control group （ P 〈 0. 05 ）, the prevalence of hypertension of the obese group was 3.88 % （20/516）. The left ventric- ular systolic function of all enrolled children were normal, the average thickness of 22 cases of the obese group whose left ventricular wall were thickened, was （ 0. 93 ± 0. 07 ） cm, and compared with the control group,the difference was not statistically significant （ P 〉 0. 05 ）. The left ventricular wall of 19 cases of obese children with hypertension were thickened, and that of 3 cases of obesity with normal blood pressure were thickened, the difference was statistically significant （ P 〈 0.05 ）. The epicardial fat thickness of obese group was （3.372 ± 0. 098 ） mm, compared with the control group, the difference was statistically significant （ P 〈 0. 001 ）. Conclusion The risk of hypertension in obese children was higher than non-obese children; obese children＇s epicardial fat thickness was significantly higher than normal weight children;the left ventric-ular wall of obese children combined with hypertension was thickening than that of normal blood pressure children.

关 键 词：肥胖 代谢综合征 高血压 左心室肥大 心包外脂肪厚度 

分 类 号：R72[医药卫生—儿科]