上海市胆囊癌流行状况和趋势分析  

Prevalence and temporal trend of gallbladder cancer in Shanghai

作　　者：张明迪[1] 龚伟[1] 郑莹[2] 张勇[1] 周迪[1] 吴春晓[2] 翁明哲[1] 杨勇[1] 全志伟[1] 

机构地区：[1]上海交通大学医学院附属新华医院普外科,上海200092 [2]上海市疾病预防控制中心肿瘤科,上海200336

出　　处：《中国实用外科杂志》2013年第8期691-694,共4页Chinese Journal of Practical Surgery

摘　　要：目的分析上海市胆囊癌的流行病学特征。方法利用上海市肿瘤登记报告和随访管理系统收集的胆囊癌发病资料，运用年度变化百分比对上海市1973—2006年胆囊癌发病的时间趋势进行分析，并与其他国家的流行病学资料进行比较。结果2002—2006年，上海全市共新诊断胆囊癌5253例，总粗发病率为7．81／10万，标化发病率为3．80／10万。上海市胆囊癌发病率男性居恶性肿瘤的第15位、女性居第11位，男女发病比为1：1．77。70岁以下的胆囊癌病例中，郊区病人年龄别发病率略高于市区病人；而70岁以上的病例，市区病人年龄别发病率明显高于郊区病人。75．1％的病例集中在〉65岁年龄组，80～84岁组的发病率最高。1973—2006年，上海市区男性和女性的标化发病率分别上升141．1％和137．6％。结论上海市的胆囊癌发病已明显超过世界中等水平，粗发病率和标化发病率的明显上升与人口老龄化有密切关系。对高发人群的全面筛查是目前预防胆囊癌惟一有效的人群干预方法。Objective To analyze the epidemiological pattern of gallbladder cancer in Shanghai. Methods The data of gallbladder cancer incidence in Shanghai were collected by the Shanghai cancer registry center and the trend of the incidence in urban Shanghai population from 1973 to 2006 was assessed by using the annual percent change （APC） analysis, which were compared with epidemiological data from other countries. Results A total of 5 253 new cases of gallbladder cancer were diagnosed from 2002 to 2006 with a crude incidence of 7.81 per 100,000 and an age-adjusted incidence of 3.80 per 100,000. Gallbladder cancer ranked the fifteenth among the common cancer in the male and ranked the eleventh in the female. The male/female incidence ratio was 1：1.77. In the age group of below 70 years, incidence is higher in the rural area than that in the urban area. But in the group of over 70 years, that is on the contrary. Of all the patients, 75.1% was over 65 years old and the highest incidence was observed in the age group of 80-84 years. The age-adjusted incidence rates have increased by 141.1% and 137.6% in the male and the female from 1973 to 2006 in urban Shanghai respectively. Conclusions The incidence of gallbladder cancer in the Shanghai area is obviously beyond the middle level of the world. Comprehensive screening of high-risk groups might be the only effective population-based preventive measure of the gallbladder cancer.

关 键 词：胆囊癌 发病率 流行病学特征 

分 类 号：R6[医药卫生—外科学]