止咳药水依赖与低磷血症的回顾性调查  

Retrospective research of hypophosphatemia in cough syrup addicts

作　　者：马松梅[1] 黄伟华[1] 肖晓山[1] 

机构地区：[1]广东省第二人民医院麻醉科,广州510317

出　　处：《中国药物滥用防治杂志》2013年第4期209-211,共3页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨止咳药水依赖与低磷血症的关系。方法:采用回顾性调查方法,收集2008年5月.-2012年12月在广东省第二人民医院住院治疗的止咳药水依赖患者506例,并随机抽查同期健康体检者500人作为对照,观察比较两组的一般资料、血磷、碱性磷酸酶(ALP)水平。结果:病例组血磷水平显著低于正常对照组,差异有统计学意义(P<0.05);病例组碱性磷酸酶水平显著高于对照组,差异有统计学意义(P<0.01)。结论:长期滥用止咳药水可致低磷血症。Objective：To investigate the relationship between hypophosphatemia and cough syrup. Methods： A retrospective analy- sis was performed in 506 cough syrup addicts treated from May 2008 to Dec. 2012. A control group of 500 healthy subjects. The gener- al data and the level of serum inorganic phosphorus, ALP were compared in those patients and 500 healthy control subjects. Results： The serum inorganic phosphorus level significantly lower in the case group than in the control group,there was significant difference be- tween two groups （P 〈 0.05 ） ; The serum ALP level was significantly higher in the case group than in the control group （ P 〈 0.01 ） ~ Conclusion： Hypophosphatemia may be associated with cough syrup abuse.

关 键 词：止咳药水依赖 低磷血症 回顾性研究 

分 类 号：R595.3[医药卫生—内科学]