急性心肌梗死患者超敏C反应蛋白和N末端-脑钠肽前体的临床观察  

Clinical Observation of High Sensitivity C-reactive Protein and N-terminal Pro-brain Natriuretic Peptide in Patients with Acute Myocardial Infarction

作　　者：吴红栋[1] 吴莎莎[1] 张研[1] 李政[1] 朱卫民[1] 石理[1] 

机构地区：[1]暨南大学附属珠海医院急诊科,519000

出　　处：《岭南急诊医学杂志》2013年第4期259-260,263,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨急性心肌梗死(AMI)患者急性期超敏C反应蛋白(hs-CRP)和N-末端脑钠肽前体(NTproBNP)水平及其临床意义。方法:将AMI患者76例分为ST段抬高急性心肌梗死(STEMI组,n=53)和非ST段抬高急性心肌梗死(NSTEMI组,n=23),并以健康者对照(C组,n=20),就诊时立即检测血浆hs-CRP浓度和NTproBNP水平。结果:STEMI组血浆hs-CRP、NT-proBNP均显著高于NSTEMI组和对照组(P<0.01)。结论:AMI患者血浆hs-CRP和NT-proBNP水平在急性期显著升高,并与心肌缺血的严重程度相关。Objective： To explore the levels and clinical significance of high sensitivity C-reactive protein （hs- CRP） and plasma N-terminal pro-brain natriuretic peptide （NT-proBNP） in patients with acute myocardial infarction （AMI）. Methods： 76 patients with AMI were divided into STEMI group（n=53） and NSTEMI group（n=23）, while healthy adult as control group（n=20）, hs-CRP and NT-proBNP were measured immediately after the patients with AMI arriving the emergency room. Results： Compared with the control group and NSTEMI group,plasma hs-CRP, NT- proBNP significantly increased in STEMI group （P〈0.01）. Conclusion： The hs-CRP and NT-proBNP elevated on the early stage in patients with AMI, and had a positive correlation to the degree of the myocardial ischemia.

关 键 词：急性心肌梗死 超敏C反应蛋白 N-末端脑钠肽前体 

分 类 号：R542.22[医药卫生—心血管疾病]