ABO溶血病新生儿178例血清学检测及其意义探讨  

ABO Hemolytic Disease Neonatal 178 Cases of Serology Detection and This Paper Probes into the Significance

作　　者：甘志远[1] 苏国红[1] 伍焕秀[2] 

机构地区：[1]广西南宁市妇幼保健院遗传科,南宁530011 [2]广西壮族自治区人民医院输血科,南宁530022

出　　处：《中国医药导刊》2013年第6期1047-1048,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察探讨ABO溶血病新生儿的血清学检测结果,总结其临床意义。方法:选取我院2009年3月～2011年3月178例疑似ABO溶血症的新生儿,分别进行血清游离抗体试验、红细胞抗体释放试验、直接抗人球蛋白试验三项试验,观察检测结果。结果:178例新生儿中,母亲血O型,新生儿血A型有104例,新生儿血B型有74例,两组不同血型的新生儿血清学三项试验检出阳性率比较无显著差异(P>0.05),无统计学意义;其中以红细胞抗体释放试验的阳性检出率最高,其次是直接抗人球蛋白试验,明显高于血清游离抗体试验,差异显著(P<0.01),具有统计学意义。结论:在血学清三项试验中,红细胞抗体释放试验、直接抗人球蛋白试验应用性较广,出结果相对较快,操作简便,能够为临床早期筛查并防治新生儿ABO溶血提供及时、可靠的依据。Objective：Observation to explore ABO hemolytic disease of the newborn serology test results,and to sum up the clinical significance.Methods：Select from March 2009 to March 178 suspected ABO hemolytic disease of the newborn,separately serum free antibody test,erythrocyte antibody release test,direct against human globulin test three test,observation test results.Results：178 newborns,mother’s blood type O,neonatal blood typeA 104 cases,the newborn blood type B 74 cases,two groups of different type of neonatal serology three test detection positive rate is no significant difference（P〈0.05）,no statistical significance;The erythrocyte antibody release test positive detection rate was the highest,direct against human globulin test,is obviously higher than that of the serum free antibody test,significant.Conclusion：In the blood learn qing three test,the erythrocyte antibody release test,direct against human globulin test applicability is wide,the relatively fast,easy operation,can for clinical early screening and prevent the neonatal ABO hemolytic provide timely and reliable basis.

关 键 词：ABO溶血 新生儿 血清学 血型 

分 类 号：R722.1[医药卫生—儿科]