超声造影在结节性甲状腺肿背景下良恶性结节鉴别诊断中的应用价值  

Application of contrast-enhanced ultrasonography for differentiation between benign and malignant thyroid nodules in patients with nodular goiter

作　　者：孔凡雷[1] 包凌云[1] 雷志锴[1] 黄安茜[1] 朱罗茜[1] 许亮[1] 

机构地区：[1]杭州市第一人民医院超声影像科,310006

出　　处：《浙江医学》2013年第14期1333-1335,共3页Zhejiang Medical Journal

基　　金：杭州市医药卫生科技计划项目(2010A001);杭州市科技计划引导项目(2011)

摘　　要：目的探讨超声造影在结节性甲状腺肿背景下良、恶性结节鉴别诊断中的应用价值。方法对结节性甲状腺肿疾病中的105个可疑结节均进行超声造影检查,分析其增强特点,所有病灶均经手术病理结果证实。结果恶性结节主要呈低增强(44.8%,30/67),良性结节主要呈等增强(39.5%,15/38),差异有统计学意义(P<0.05);良、恶性结节均以不均匀增强表现为主(60.5%、68.7%),差异无统计学意义(P>0.05)。恶性结节主要呈慢进同出(62.7%,42/67),良性结节主要呈同进同出(50%,19/38),差异具有统计学意义(P<0.01)。结论超声造影对鉴别结节性甲状腺肿背景下良、恶性结节有一定的诊断价值。Objective TO evaluate the application of contrast-enhanced ultrasonography （CEUS） in differential diagnosis between benign and malignant thyroid nodules in patients with nodular goiter. Methods One hundred and five suspected thy- roid nodules in patients with the nodular goiter were examined by CEUS. The enhanced characteristics of the nodules were ana- lyzed and the pathological diagnosis was obtained from surgically resected nodules. Results The dominant enhanced pattern was isoenhancement for benign thyroid nodules （39.5%, 15/38） and hypoenhancement for the malignant one （44.8%, 30/67） re- spectively. There was significant difference of the enhanced pattern between benign and malignant nodules（P〈0.05）. Most of the nodules appeared as heterogeneous enhancement both in benign（60.5%） or malignant （68.7%） ones. Most of the malignant nod- ules （62.7%, 42/67） presented ＂wash-in slowly＂ and ＂wash-out simultaneously＂ signs, whereas 50% of the benign nodules ap- peared as ＂wash-in simultaneously＂ and ＂wash-out simultaneously＂ signs（P〈0.01）. Conclusion CEUS is valuable in the diagno- sis of benign and malignant thyroid nodules in patients with nodular goiter.

关 键 词：结节性甲状腺肿 超声检查 超声造影 

分 类 号：R445.1[医药卫生—影像医学与核医学]