卵巢创伤后电凝止血对卵巢储备功能影响的实验研究  

Experimental Research on the Influence of Ovarian Post-traumatic Reserve Function with Electric Coagulation Hemostasis

作　　者：张燕燕 刘淑丽 吴丽慧 

机构地区：[1]广东省汕头市潮阳区大峰医院,515154

出　　处：《医学理论与实践》2013年第16期2101-2102,共2页The Journal of Medical Theory and Practice

摘　　要：目的:通过采用家兔做研究对象,了解创伤后电凝止血是否会加快卵巢功能的衰退,从而为临床上围手术期卵巢手术后卵巢功能的保护提供有价值的资料。方法:选取性成熟雌性新西兰兔32只,随机分4组:单极电凝止血组、双极电凝止血组、缝扎止血组、空白对照组,每组8只。模拟人腹腔镜下对卵巢创面电凝止血,并与对照组相比。观察4组术前及术后4周性激素水平、卵巢重量、术后坏死区域面积、卵泡分类记数情况。结果:与术前相比,术后4周性激素水平无明显变化,差异无统计学意义(P>0.05),处理各组间术后4周卵巢重量、术后坏死区域面积、成熟卵泡记数对比无明显差异,差异无统计学意义(P>0.05)。但是双极电凝止血组手术止血时间明显较其他两组短,差异有统计学意义(P<0.05)。结论:腹腔镜下卵巢手术中三种止血方式对围手术期卵巢功能影响不明显,但是双极电凝止血在手术时间上明显优势于单极电凝止血及缝扎止血。Objective：By using the rabbit as study object,investigate if the post-traumatic operation with the electric coagulation hemostasis accelerates the decline of ovarian function,and thereby provide valuable information for the clinical protection of ovarian functions after perioperative ovarian surgery.Methods：Selected 32sexually mature female New Zealand rabbits and separated them into four groups randomly with 8rabbits in each group：unipolar coagulation hemostasis,bipolar coagulation hemostasis,suture hemostasis,no procedure.Applied electric coagulation hemostasis on the ovarian wound under the simulated human laparoscopic,and compared with the no-procedure group.Observed the four groups,before and four weeks after operation respectively,on the sex hormone levels,ovary weight,postoperative necrosis area,the classification of the follicle count.Results：Compared with the preoperative data,there was no obvious change in sex hormone levels four weeks after operation;there was no statistics significance（P0.05）.There was neither significant difference among the four groups on the ovary weight,postoperative necrosis area,and the classification of the follicle count four weeks after the operations.The differences are not statistically significant（P0.05）.However,the surgery hemostasis of the bipolar coagulation takes obviously shorter time than the other two surgery groups;the difference was statistically significant（P0.05）.Conclusion：The three hemostatic ways separately used in the laparoscopic ovarian surgeries have no obvious difference in their impact on perioperative ovarian function,but the bipolar coagulation hemostasis approach has the advantage of shorter operation time than the unipolar coagulation hemostasis and suture.

关 键 词：腹腔镜 卵巢手术 手术期间 止血方式 卵巢功能 

分 类 号：R713.6[医药卫生—妇产科学]