地尔硫缓释片治疗高血压37例  

Effect of Diltizem Sustained Release Tablet in Treatment of Essential Hypertension (37 Cases of Report)

作　　者：张宝珍[1] 黎明江[1] 汪冬萍[1] 胡成林[1] 

机构地区：[1]湖北医科大学附属第一医院心内科,武汉430060

出　　处：《医药导报》2000年第3期230-231,共2页Herald of Medicine

摘　　要：探讨地尔硫缓释片对轻、中度高血压患者疗效和耐受性。方法 :采用地尔硫缓释片 90～ 180mg ,qd。结果 :37例患者经 8周治疗 ,血压较治疗前下降了 (3 .0 7± 1.6 6 ) (2 .0 2± 0 .94)kPa(P <0 .0 1) ,显效率 81.1% ,总有效率 97.3 %。 16例病人接受了动态血压监测 ,结果显示 2 4h平均血压较治疗前分别下降了 2 .71 1.5 7kPa(P <0 .0 1) ,收缩压与舒张压的谷峰比值分别为 6 6 .6 % ,76 .0 %。结论 :地尔硫缓释片是有效且易于耐受的抗高血压药物。Objective:To observe the efficacy of diltizem sustained release (SR) tablet in treatment of mild to moderate essential hypertension. Method:Diltizem SR tablet was given 90-180 mg once daily. Result:After 8 weeks, these patients' SBP and DBP were significantly reduced by (3.07±1.66) kPa and (2.02±0.94) kPa (P<0.01), respectively. The markedly effective rate was 81.1%, and total effective rate was 97.3%. 16 of the patients received 24-hour AMBP, their BP was averagely reduced by 2.71/1.57 kPa, and both T/P rafio wre 66.6% (SBP) and 76.0% (DBP), respectively. Conclusion:Diltizem SR tablet is effective and well-toleraled in the treatment of patients with essential hypertension.

关 键 词：地尔硫Zhuo缓释剂型 高血压 药物疗法 

分 类 号：R544.105[医药卫生—心血管疾病] R972.4[医药卫生—内科学]