络活喜联合苯那普利对中老年高血压合并NIDDM患者的疗效观察  

Effect of norvasc and benazepril for treatment elderly hypertensive patients with NIDDM

作　　者：伏忠阳 朱海燕[2] 

机构地区：[1]武警边防部队士官学校门诊部,昆明650214 [2]中国人民解放军总医院内急诊科,北京100853

出　　处：《重庆医学》2013年第24期2829-2831,共3页Chongqing medicine

基　　金：国家自然科学基金资助项目(30900543)

摘　　要：目的探讨络活喜联合苯那普利对中老年高血压合并非胰岛素依赖型糖尿病(NIDDM)患者的治疗效果。方法以2009年3月至2012年5月本院收治的52例中老年高血压合并NIDDM患者为研究对象,随机分成观察组和对照组各26例。其中观察组患者接受络活喜联合苯那普利的治疗方案,对照组患者接受单用络活喜的治疗方案,对两种治疗方案的临床疗效进行评估。结果治疗8周后,观察组患者的收缩压及舒张压明显低于对照组,差异有统计学意义(P<0.05);8周后观察组患者空腹血糖、餐后2h血糖水平以及空腹胰岛素水平明显低于对照组,胰岛素敏感指数明显高于对照组,差异有统计学意义(P<0.05)。结论络活喜联合苯那普利的治疗方案可以有效控制中老年高血压合并NIDDM患者的血压和血糖,并改善患者的胰岛素抵抗,效果优于单一运用络活喜,值得在临床实践中加以推广应用。Objective To investigate the effect of Norvasc combined with Benazepril for treatment elderly hypertensive patients with Non-insulin-dependent diabetes mellitus.Methods 52 cases of elderly hypertensive patients with Non-insulin-dependent diabetes mellitus were selected as the study object and were randomly divided into the observation group and the control group,each with 26 cases of patients.The observation group was given Norvasc combined with Benazepril while the control group was given Norvasc.Results After 8 weeks,the SBP and DBP of the observation group were significantly lower than that of the control group（P0.05）.The FBG and 2h PBG were significantly lower than that of the control group as well as the ISI significantly higher（P0.05）.Conclusion Norvasc combined with Benazepril can effectively control the blood pressure and plasma glucose of elderly hypertensive with Non-insulin-dependent diabetes mellitus,also improve the ISI of patients.It is deserved to be promoted widely in the clinical work.

关 键 词：络活喜 苯那普利 高血压 非胰岛素依赖型糖尿病 

分 类 号：R544.1[医药卫生—心血管疾病]