武汉市某医院新生儿院内真菌感染现况调查  

Investigation on the Nosocomial Fungal Infection of Neonates in a Hospital,Wuhan

作　　者：凃敏[1] 陈英[1] 王华[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院院感科,武汉430030

出　　处：《医学与社会》2013年第8期26-27,共2页Medicine and Society

摘　　要：目的:为了预防和减少新生儿院内真菌感染,提出有效防治措施。方法:采用回顾性调查方法,对武汉市某医院2008年1月-2012年12月新生儿病房发生院内真菌感染的情况进行调查分析。结果:新生儿院内真菌感染发病率为4.2%,感染菌株以近平滑假丝酵母菌为最常见,其次为白假丝酵母菌;常见菌株对常用抗真菌药均出现了部分耐药;发生新生儿院内真菌感染的独立危险因素为:极早产儿(孕龄<32周)、极低出生体重儿(BW<1500g)、深静脉留置导管、气管插管、使用广谱抗菌药物>5d及细菌性败血症。结论:新生儿院内真菌感染发病率仍较高,医务人员应严格执行消毒隔离措施和手卫生,减少侵入性操作,合理使用抗菌药。Objective ：To provide scientific basis for effective prevention and treatment of neonatal nosocomial fungal infections. Methods： A retrospective survey was used to investigate the nosocomial fungal infections in neonates in a hospital from January 2008 to December 2012. Results：The incidence of neonatal nosocomial fungal infections was 4.2%. The most common infection strains were Candida parapsilosis, followed by Candida albinos ;The common strains showed partial resistance to commonly used antifungal agents;The independent risk factors of neonatal nosocomial fungal infections were ： very preterm infants （ gestational age 〈 32 weeks ） , very low birth weight infants （ BW 〈 1500g ） , deep venous catheter, endotracheal intubation, the use of broad - spectrum antimicrobial agents 〉 5 d and bacterial sepsis. Conclusion：The incidence of nosocomial fungal infection is still higher in neonatal department. Medical workers should take the measures of disinfection and isolation measures and hand hygiene strictly. The invasive procedures should be reduced, and antimicrobial agents should be used rationally.

关 键 词：新生儿 院内感染 真菌 

分 类 号：R197.32[医药卫生—卫生事业管理]