用于神经记录的镍铬合金微丝电极输入输出特性研究  

Researches on the Input-output Properties of Neural Recording Ni-Cr Alloy Microwire Electrodes

作　　者：师黎[1] 杨巍[1] 王松伟[1] 

机构地区：[1]郑州大学电气工程学院,郑州450001

出　　处：《科学技术与工程》2013年第22期6443-6449,共7页Science Technology and Engineering

基　　金：国家自然科学基金项目(60971110);河南省科技攻关计划项目(122102210102)资助

摘　　要：从传感器应用的角度出发,对用于神经记录的自制镍铬合金微丝电极输入输出特性进行体外研究。根据胞外神经记录机理对决定微丝电极输入量和输出量的各个因素进行分析,构建了包含生物电位、热噪声、半电池电位和前段放大器等组分的微丝电极等效记录电路;基于等效电路,结合测量的电极电化学阻抗谱从交流特性、噪声特性和直流基线漂移三个方面对镍铬合金微丝电极的输入输出特性进行研究。结果表明在生物电的频率带宽范围内(300—6 000 Hz),自制的镍铬合金微丝电极的交流幅值增益不低于0.97,相位偏移不超过2.5度,生物电频带内热噪声导致的电压均方根约为8 mV。In terms of the methodology of sensors,research on the input-output property of Nickel Alloy Micro Wire Electrodes is processing.Based on the extracellular neural recording mechanism and factors which affect the input-output relationship of the biosensor,the equivalent circuit of extracellular recording including biopotential,thermal noise,static Nernst potential and amplifer is constructed.Based on the electrochemical impendence spectra,the ac property,noise property and dc baseline drift of microwire electrodes are researched.That is,within frequency bands which contain the electroneurogram band（ENG,300 ～ 6 000 Hz）,the ac amplitude gain is no fewer than 0.97,the phase-shift is not more than 2.5 degree,the RMS voltage due to thermal noise is about 8 μV.

关 键 词：输入输出特性 镍铬合金 微丝电极 胞外神经记录机理 

分 类 号：TM241.2[一般工业技术—材料科学与工程]