我院178例药品注射剂不良反应报告分析  

Analysis of 178 cases of injection aderse drug reaction reports in our hospital

作　　者：李杰 李晓宏 杨新峰 杨海宁 李晓霞 

机构地区：[1]武警青海总队医院,青海西宁810000

出　　处：《武警后勤学院学报（医学版）》2013年第7期616-618,共3页Journal of Logistics University of PAP（Medical Sciences）

摘　　要：【目的】了解我院注射剂药品不良反应(adverse drug reaction,ADR)发生的特点及一般规律,开展药物警戒,减少不良反应发生,为临床合理用药提供参考。【方法】汇总统计我院2012年上报的178例注射剂ADR,对患者情况、药品种类、注射方法、累及器官或系统及临床表现等进行统计、分析。【结果】178例ADR报告中涉及的药物品种共有70种,其中抗感染药类药物19种(27.14%),居引发ADR的品种数首位;ADR发生以大分子量药物、中药复方制剂、抗感染药最为常见;ADR累及器官或系统以皮肤及其附件最为常见。【结论】临床使用注射剂应关注药物的种类、适用人群、临床表现等,了解药品不良反应发生机制,加强ADR监测报告工作,确保药物治疗安全、有效。[Objective]To investigate the characteristics and regulations of adverse drug reaction （ADR） in our hospital ,Development of pharmacovi,to reduce adverse reactions, Provide references for clinical rational drug use. [Methods]Summary statics in our hospital in 2012 178 cases of ADR injection.on the condition of patients,the kind of drugs,injection method,involved organs or systems and clinical manifestations such as statics,analysis. [Results] 178 cases of ADR involving a total of 70 kinds of drugs,the anti-infective in 19 （27.14%）,in the firet initiator ADR;ADR occurred in large molecular weight,the compound preparation of traditional Chinese medicine, antibiotics are the most common; ADR mainly involved organs or systems to the skin and its appendages are the most common. [Conclusion] Clinical attention should be paid to the types of drugs,is suitable the crowd clinical manifestation,Understanding of adverse drug reaction mechanism,strengthen the ADR monitoring work,ensure the drug safety,effective.

关 键 词：药物不良反应 注射剂 统计 分析 监测 

分 类 号：R917[医药卫生—药物分析学]