胚胎期暴露手机辐射对仔鼠脑组织NO和SOD的影响  

Effect of exposure to mobile phone radiation during embryonic period on NO and SOD in cerebral tissue of newborn mice

作　　者：田会宾[1] 廖珩[2] 吴再辉[1] 许斌[1] 马俊利[3] 

机构地区：[1]唐山钢铁集团有限责任公司医院,河北唐山063020 [2]唐山工人医院 [3]唐山职业技术学院

出　　处：《中国妇幼保健》2013年第22期3656-3657,共2页Maternal and Child Health Care of China

基　　金：河北省2010年科技支撑计划课题〔10276128〕

摘　　要：目的:探讨胚胎期暴露手机辐射对仔鼠脑组织NO和SOD的影响。方法:将22只孕鼠分为3组,2个实验组母鼠妊娠全程暴露于手机辐射,对照组母鼠未暴露于手机辐射下。分娩8周后应用酶免疫标记技术测定暴露组和对照组仔鼠脑组织NO含量和SOD活性。结果:胚胎期暴露手机辐射仔鼠脑组织中NO含量高于对照组(P<0.05),SOD活性低于对照组(P<0.05)。时分多址组与码分多址组间NO含量及SOD活性比较,均无统计学差异(P>0.05)结论:胚胎期暴露手机辐射可能引起仔鼠脑组织中NO浓度上升,SOD活性降低。Objective： To explore the effect of exposure to mobile phone radiation during embryonic period on NO and SOD in cerebral tissue of newborn mice.Methods： Twenty-two pregnant mice were divided into three groups,the pregnant mice in two experimental groups were exposed to mobile phone during the whole pregnant period,while the pregnant mice in control group were not exposed to mobile phone.At eight weeks after delivery,enzyme immune labeled technique was used to detect NO contents and SOD activities in cerebral tissue of newborn mice in experimental groups and control group.Results： NO contents in cerebral tissue of newborn mice in two experimental groups were statistically significantly higher than that in control group（P 0.05）,while SOD activities were statistically significantly lower than that in control group（P 0.05）.There was no statistically significant difference in NO content and SOD activity between TDMA group and CDMA group（P 0.05）.Conclusion： Exposure to mobile phone during embryonic period may induce increase of NO content and decrease of SOD activity in cerebral tissue of newborn mice.

关 键 词：手机辐射 胚胎 NO SOD 

分 类 号：R76[医药卫生—耳鼻咽喉科]