无溶剂超声辐射下磷钨酸铈催化合成5-亚烃基-2,2-亚戊基-1,3-二噁烷-4,6-二酮  

Solvent-Free Synthesis of 5-Alkenyl-2,2-pentamethylene1,3-dioxane-4,6-diones under Ultrasonic Irradiation with CePW_(12)O_(40)as Catalyst

作　　者：许招会[1] 林春花[1] 

机构地区：[1]江西师范大学化学化工学院,南昌330027

出　　处：《有机化学》2013年第7期1540-1544,共5页Chinese Journal of Organic Chemistry

基　　金：国家科技攻关计划(No.2001BA323C);江西省研究生创新基金(No.YC10A051)资助项目~~

摘　　要：在CePW12O40催化下,芳香醛和2,2-亚戊基-1,3-二噁烷-4,6-二酮在无溶剂条件下经超声辐射合成了8种5-亚烃基-2,2-亚戊基-1,3-二噁烷-4,6-二酮.当催化剂的用量为5%(摩尔分数)时,室温反应20～35 min,收率为87.6%～94.1%.此外,还探讨了CePW12O40的可能催化机理.该方法具有条件温和,反应时间短且收率高的优点.催化剂CePW12O40对环境友好且可循环利用.Eight kinds of 5-alkenyl-2,2-pentamethylene-1,3-dioxane-4,6-diones were synthesized by the Knoevenagel con- densation reaction of aromatic aldehydes with 2,2-pentamethylene-l,3-dioxane-4,6-dione using CePW12040 as catalyst, with- out solvent under ultrasonic irradiation. The results indicate that the yields ranged from 87.6% to 94.1% when using 5% （molar fraction） CePWI2040 and reacting at room temperature for 20-35 min. Furthermore, a proposed reaction mechanism for the reaction catalyzed by CePW12040 was speculated. Compared to the classical Knoevenagel condensation reaction, the main advantages of the present procedure were milder conditions, shoiter reaction time and higher yields, which afforded an effec- tive method to synthesize 5-alkenyl-isopropylidene malonate derivatines. Further study showed that CePW12040 was environ- mentally friendly and reused for four times without any noticeable decrease in the catalytic activity.

关 键 词：2 2-亚戊基-1 3-二噁烷-4 6-二酮 磷钨酸铈 芳香醛 缩合反应 

分 类 号：O626[理学—有机化学]