定量脑电图在重型颅脑创伤患者预后评估中的应用  

Application of quantitative EEG in predicting of prognosis in long-term unconscious patients after severe traumatic brain injury

作　　者：周月玲[1] 陈燕伟 王向宇 

机构地区：[1]南方医科大学珠江医院神经内科脑电图室,广州市510282 [2]神经外科

出　　处：《实用医学杂志》2013年第15期2482-2485,共4页The Journal of Practical Medicine

摘　　要：目的:应用定量脑电图分析伴长期意识障碍的重型颅脑创伤患者临床预后。方法:将我院41例意识障碍超过2周的重型颅脑创伤患者通过6个月的观察以GOS评分分为预后良好组及预后不良组,选取同期20例正常成人作为对照组。均予以脑电图检查并获取原始资料后采用计算机软件进行快速傅里叶转换功率谱分析。通过计算δ、θ、α1、α2、βl、β2 6个频带的相对的功率值(δ+θ)/(α+β)值,并以(δ+θ)/(α+β)值当作预后评判指标,从而研究3组间GOS评分的差异及影响。结果:θ频带对应的功率对所得方程无贡献,为剔除变量。其余指标对GOS评分相关程度的顺序为:(δ+θ)/(α+β)值、δ、β及α所对应相对功率值,以(δ+θ)/(α+β)值对GOS评分的影响最大(P=0.006)。各指标间差异具有显著统计学意义(P=0.000)。结论:定量脑电图以其经济快速、客观实用的特点,可作为预测颅脑创伤患者预后的一种客观、准确的工具。Objective To evaluate the quantitative electroencephalography in the prognosis of the long- term unconscious patients after severe traumatic brain injury. Methods 41 cases with consciousness disorders for more than two weeks who received 6 months clinical observation after severe traumatic brain injury were divided into good prognosis group and a poor prognosis group by GOS scores. 20 cases of normal adults were selected in the same way as a control group. The obtained data of all cases by EEG were analyzed by Fast Fourier transform software. The difference and effect of GOS grade among the three groups were obtained by calculating relative power of bandwidth δ, θ, α1, α, β1, β and （δ＋θ）/（α＋β） and selecting （δ＋θ）/（α＋β） as prognosis indicator. Results The relative power of bandwidth 0 has no contribution to the equation and the variable need to ignore. The relative power order of the degree of correlation with the GOS of the remaining indexes are （δ＋θ）/（α＋β） value, δ, β and α. The value of （δ＋θ）/（α＋β） is the one that affects most （P = 0.006）. The differences among theses indexes were statistically significant （P = 0.000）. Conclusion As an economic, objective and rapid method for the evaluation of brain function, the QEEG can be a objective, accurate tool to predict the prognosis of patients with traumatic brain injury.

关 键 词：颅脑损伤 定量脑电图 预后 

分 类 号：R651.15[医药卫生—外科学]