异叶三宝木叶的化学成分研究(英文)  

Chemical Constituents from the Leaves of Trigonostemon flavidus

作　　者：唐贵华[1,2] 张于[1] 何红平[1] 郝小江[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650201 [2]中国科学院大学,北京100049

出　　处：《天然产物研究与开发》2013年第7期912-915,共4页Natural Product Research and Development

基　　金：supported by the National Natural Sci-ence Foundation of China(21072199);Natural Science Funding ofYunnan Province(No.2009CD112);Foundation of Chinese Acad-emy of Sciences to Dr.H.P.He,the Yong Academic and TechnicalLeader Raising Foundation of Yunnan Province(2010CI047)

摘　　要：从异叶三宝木(Trigonostemon flavidus)叶中分离得到9个化合物,经波谱数据分析鉴定为robustic acid(1),1-[6-hydroxy-2-methoxy-2″,2″-dimethylpyrano-(5″,6″:3,4)]-2-(4'-methoxyphenyl)-1,2-ethanedione(2),3β-ursolic acid(3),(6S,7E)-6-hydroxy-4,7-megastigmadien-3,9-dione(4),3(-hydroxy-5,6-epoxy-7-megastigmen-9-one(5),(3R,6R,7E)-3-hydroxy-4,7-megastigmadien-9-one(6),loliolide(7),methyl P-coumarate(8),和methyl si-napate(9)。化合物1～7和9为首次从三宝木属(Trigonostemon)植物中分离得到。Nine known compounds were isolated from the leaves of Trigonostemon flavidus. On the basis of spectroscopic data, their structures were identified as robustic acid （ 1 ）, 1-[ 6-hydroxy-2-methoxy-2＂, 2＂-dimethylpyrano-（ 5＂, 6＂： 3, 4 ） ] -2- （4＇-methoxyphenyl） -1,2-ethanedione （2）, 3/3-ursolic acid （ 3 ）, （ 6S, 7E） -6 -hydroxy-4,7-megastigmadien-3,9 - dione （4）, 3/3-hydroxy-5,6-epoxy-7-megastigmen-9-one （5）, （ 3R, 6R,7E ） -3-hydroxy-4,7-megastigmadien-9-one （ 6 ）, loliolide （7） ,methyl P-coumarate （8）, and methyl sinapate （9）. Compounds 1-7 and 9 were obtained from the genus Trigonostemon for the first time.

关 键 词：大戟科 异叶三宝木 化学成分 黄酮 降倍半萜 

分 类 号：R284.1[医药卫生—中药学] Q946.91[医药卫生—中医学]