乐山市手足口病病原学检测结果及影响因素分析  

Analysis of the results of etiology detection of hand-foot-mouth disease and its influencing factors in Leshan city

作　　者：秦利平[1] 谢应国[1] 罗瑶[1] 江顿滔[1] 

机构地区：[1]乐山市疾病预防控制中心,四川乐山614000

出　　处：《现代预防医学》2013年第15期2923-2924,2940,共3页Modern Preventive Medicine

摘　　要：目的探讨和分析乐山市手足口病病原学检测结果及其影响因素。方法利用Real-timeRT-PCR方法检测手足口病肠道病毒核酸,并对检测结果可能的影响因素进行分析。结果 390份咽拭子标本中,手足口病肠道病毒核酸检测总阳性率为26.2%;核酸检测的阳性率与检测试剂的种类无关,但与采样日期与发病日期、送样日期与采样日期以及检测日期与送样日期之间的时间间隔有关,还与是否在高峰季节采样有关。结论该市手足口病病原以CVA16和EV71为主,在高峰季节采样以及病例发病后及时采样、及时送样并及时检测,可以提高手足口病肠道病毒核酸检测的阳性率。OBJECTIVE To analyse the results of etiology detection of HFMD and its influencing factors in Leshan city. METHODS The method of real-time RT-PCR was used to detect the enterovirus nucleic acid of HFMD. SPSS was used to analyse the data. RESULTS The positive rate of pan-enterovirus nucleic acid of HFMD was 26.2% in 390 throat swab specimens. HFMD virus detection rate was not related to the types of reagent. There was a relationship with the time interval between sampling and disease onset, transferring and sampling, detection and transferring. It was related to the sampling seasons too. CONCLUSION The HFMD in Leshan is mainly caused by EV71 and CVA16. It’ll improve the detection rate if we sample, transfer and detect timely in the peak season of HFMD.

关 键 词：手足口病 病原学 影响因素 

分 类 号：R512.5[医药卫生—内科学]