脾胃与鼻鼽发病机制的临床研究  

Clinical study of spleen and stomach with pathogenesis of allergic rhinitis

作　　者：范愈燕[1] 佘文煜 王向东[3] 锡琳 支楠[1] 张善冬[1] 张罗[2,3] 

机构地区：[1]首都医科大学附属北京同仁医院传统医学科,北京100730 [2]北京市耳鼻咽喉研究所耳鼻咽喉科,北京100005 [3]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京100730

出　　处：《北京中医药》2013年第6期428-430,共3页Beijing Journal of Traditional Chinese Medicine

基　　金：国家杰出青年科学基金(81025007);首都医科大学基础临床课题(11JL39)

摘　　要：目的以临床调查问卷为依据,论述脾胃与鼻鼽发病机制的相关性。方法收集2011年5月—2012年5月首都医科大学附属北京同仁医院耳鼻喉科变态反应中心就诊的15岁以上的鼻炎患者1252例,对其进行问卷调查,对1008例完成问卷调查者以致敏原皮肤点刺试验及临床症状分为变应性鼻炎组649例和非变应性鼻炎组359例。结果变应性鼻炎合并消化系统疾病209例(32.3%),合并神经官能症234例(36.1%);非变应性鼻炎合并消化系统疾病136例(37.9%),合并神经官能症179例(49.9%),变应性鼻炎组及非变应性鼻炎组均具有消化系统疾病及神经官能症高发病史。结论脾气虚是鼻鼽发病的主要病机,脾胃与鼻鼽发病有密切的关系。Objective To explore the relationship of spleen and stomach with pathogenesis of allergic rhinitis based on the clinical questionnaire.Methods 1 252 samples over 15 years old with rhinitis were collected for questionnaire survey,who visited in the center for allergic reaction,Beijing Tongren Hospital,Capital Medical University from May in 2011 to May in 2012,and 1 008 samples who had finished the questionnaire survey were divided an allergic rhinitis group（AR group,n=649） and a non-allergic rhinitis group（NAR group,n=359） by skin prick test and clinical symptoms.Results There are 209 patients（32.3%） with digestive system disease and 234 patients（36.1%） with neurosis in the AR group,while 136 patients（37.9%） and 179 patients（49.9%） respectively in NAR group.The both groups had a medical history with high incidence in digestive system disease and neurosis.Conclusion Spleen qi deficiency is the main mechanism of allergic rhinitis,and spleen and stomach is closely associated with pathogenesis of allergic rhinitis.

关 键 词：脾胃学说 脾气虚 过敏性鼻炎 非过敏性鼻炎 

分 类 号：R276.1[医药卫生—中医五官科学]