缺血性进展型卒中相关多因素分析及与中医辨证分型关系的研究  

Analysis of Relevant multi-factor about Ischemic stroke,progressive stroke and the relationship between the multi-factor and syndrome differentiation of TCM

作　　者：尹亚东 刘书红 郑锐锋[2] 

机构地区：[1]河南省舞阳县人民医院,河南舞阳462400 [2]河南省洛阳市中心医院,河南洛阳471009

出　　处：《中国中医急症》2013年第7期1105-1107,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：河南省科技计划项目(No.0503106)

摘　　要：目的探讨缺血性卒中的进展与性别、年龄、感染因素、高血压病史、冠心病史、糖尿病史、脑梗死史、烟酒嗜好、便秘情况、血小板(PLT)、凝血酶原时间(PT)、纤维蛋白原(FIB)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、血糖(GLU)水平以及中医辨证分型的关系。方法缺血性卒中住院病人共入选427例。根据本课题制定的进展型脑卒中(SIP)标准,确定136例,非SIP 291例。记录相关资料数据,采用相应统计学方法分析研究导致卒中进展的相关因素。结果 SIP与非SIP组比较,性别、感染、高血压病史、冠心病史、糖尿病史、脑梗死史、烟酒嗜好、FIB、TG、LDL水平等因素的组间差别没有统计意义;便秘因素差异有统计学意义;PLT、PT、TC、HDL、GLU水平的组间差异有统计学意义;通过Logistic回归分析相关多因素,年龄和便秘分别进入了回归方程。两组火热证病例数组间差异有统计学意义。结论中医辨证分型的火热证、便秘因素、年龄因素、PLT、PT、TC、HDL、GLU诸因素,是缺血性卒中进展的重要危险因素。Objective：To explore the relationship between ischemic stroke,progressive stroke and gender,age,infection factors,history of hypertension,coronary heart disease,diabetes,stroke history,alcohol addiction,constipation,platelets（PLT）,prothrombin time（PT）,fibrinogen（FIB）,total cholesterol（TC）,triglycerides（TG）,high density lipoprotein（HDL）,LDL,glucose（GLU） syndrome differentiation of TCM.Results：427 patients were recruited.136 patient were defined as SIP group,while 291 patients were defined as non-SIP group,according to standard of ischemic,progressive stroke（SIP） by this issue.Relevant datas were recorded.And relevant multifactor about ischemic stroke,progressive stroke were analysed.Methods：Difference of gender,history of hypertension,coronary heart disease,diabetes,stroke history,alcohol addiction,FIB,TG,LDL between the two groups had no statistical significance,while constipation,the level of PLT,PT,TC,HDL,GLU showed statistical significance.Age and constipation came into regression equation according to Logistic regression analysis.The patients with heat syndrome between two groups showed no statistical significance.Conclusion：Heat syndrome,age,constipation,PLT,PT,TC,HDL,GLU are important risk factors about ischemic stroke,progressive stroke.

关 键 词：缺血性卒中 进展型卒中 相关因素 辨证分型 

分 类 号：R255.2[医药卫生—中医内科学]