MDCT定量评价腔内血栓形成的腹主动脉瘤瘤体弹性  

Quantitative Assessment of Abdominal Aortic Aneurysm Sac Distensibility with Intraluminal Thrombus Using Multi-Detector CT

作　　者：李莉丽[1] 查云飞[1] 李亮[1] 彭宙峰[1] 陆雪松[2] 

机构地区：[1]武汉大学人民医院放射科,430060 [2]中南民族大学生物医学工程学院,武汉430074

出　　处：《临床放射学杂志》2013年第8期1115-1118,共4页Journal of Clinical Radiology

基　　金：国家自然科学基金青年科学基金资助项目(编号:61002046)

摘　　要：目的探讨64排CT定量评价腔内血栓腹主动脉瘤瘤体弹性。方法对31例含腔内血栓腹主动脉瘤患者采用回顾性心电门控技术和分段数据采集方式行腹主动脉64排螺旋CT血管成像。将获得的原始数据在0%～95%R-R间期,间隔5%分别重组图像,采用MATLAB 7.5软件行半自动图像分割方法,然后分别测量各期相内瘤体直径、最大和最小面积及弹性D值等指标在管腔及管壁方面的变化。结果腹主动脉瘤瘤体最大直径与管壁、管腔弹性值间均无显著相关性(r分别为-0.315、-0.251,P均>0.05)。瘤体管腔弹性D值为(1.15±0.47)×10-5Pa-1,管壁弹性D值为(0.95±0.48)×10-5Pa-1,瘤体管腔D值明显高于管壁,差异具有统计学意义(P<0.05)。结论腔内血栓形成的腹主动脉瘤瘤体弹性的大小并不依赖于瘤体直径的变化,且瘤体管腔的弹性要明显高于管壁。弹性评估可以为腹主动脉瘤的诊断和治疗提供帮助。Objective To noninvasively and quantitatively evaluate the distensibility of abdominal aortic aneurysm sac （AAAs） with intralnminal thrombus using 64 MDCT. Methods 31 patients with AAAs underwent computed tomography angiography （CTA）examination. Time resolved images were acquired with the retrospective ECG-gated technology and sec- tion data acquisition mode. Scan data were reconstructed at 20 phases between 0% and 95% of the R-R intervals with an increment of 5%. Ali reconstructed images were analyzed using algorithm developed Matlab 7.5 （Version R2007b, the MathWorks, Natick, MA, USA）. At different phases, AAA sac diameter, max and minimal area, distensibility values were calculated in the lumen and wall. Results Aneurysm sac diameter had not any correlation with distensibility （ rwall = - 0.315, rlumen = - 0.251, Pwall,lumen 〉 0.05 ）. Mean distensibility of Dlumen and Dwall were （ 1.15 ±0.47 ） x 10-SPa-~ and （0.95 ±0.48） x 10-SPa-1, respectively. A significant difference of distensibility between AAA wall and AAA lumen was proved （P 〈 0.05） also by use of the Wilcoxon test. Distensibility of the AAA wall was significantly lower than that of AAA lumen. Conclusion AAA distensibility is completely independent of the aneurysm size, and the disten- sibility of lumen is significantly higher than that of wall. Distensibility assessment could be a valuble method for the diagno- sis and treatment for abdominal aortic aneurysm.

关 键 词：体层摄影术 X线计算机 腹主动脉瘤 腔内血栓 弹性 

分 类 号：R816.2[医药卫生—放射医学]