一起炭疽疫情中鼠疫F1抗体胶体金检测阳性分析  

Analysis for F1 antibodies against Yersinia pestis with colloidal gold test positive in an Anthrax case

作　　者：熊浩明[1] 郑谊[1] 魏荣杰[1] 金星[1] 汪元忠[1] 李翔[1] 冯建萍[1] 靳娟[1] 张珊瑚[1] 谢宗海[2] 魏绍振[1] 

机构地区：[1]青海省地方病预防控制所鼠疫预防控制科,青海西宁811602 [2]贵南县疾病预防控制中心

出　　处：《中国地方病防治》2013年第4期274-275,共2页Chinese Journal of Control of Endemic Diseases

基　　金：青海省科技厅应用基础研究项目(2011-Z-711)

摘　　要：目的通过对一起人间皮肤炭疽疫情中患者血清鼠疫F1抗体胶体金阳性分析,为鼠疫诊断提供借鉴。方法炭疽疫情处理过程中对患者血清鼠疫F1抗体进行鼠疫间接血凝试验(IHA)和胶体金检测。结果 2名皮肤炭疽患者2份血清鼠疫F1抗体胶体金检测阳性,鼠疫间接血凝检测试验复判结果显示阴性。结论在其他疫情处理过程中排除鼠疫时,应结合患者临床症状、流行病学调查结果及实验室检测结果综合诊断和分析。ObjectiveBased on the analysis for patients＇ serum of which F1 antibodies against Yersinia pestis colloidal gold test showed positive in a human skin anthrax case, provide references for plague diagnosis. Methods In the process of handling the Anthrax case, we tested F1 antibodies against Yersinia pestis in patients＇ serum by colloidal gold test and indirect hemagglutination test. Results The colloidal gold test for F1 antibodies against Yersinia pestis showed positive, while the indirect hemagglutination test showed negative for 2 copies of serum from 2 skin anthrax patients. Conclusions To rule out the possibility of infection of plague , clinical symptoms, epidemiological survey and laboratory testing results, comprehensive diagnosis and analysis should be combined for reference.

关 键 词：鼠疫 F1抗体 胶体金 免疫层析 

分 类 号：R418.1[医药卫生—临床医学] R516.8