中老年单纯收缩期正常高值血压与冠心病的关系  

Relation of Isolated Systolic High-Normal Blood Pressure and Coronary Heart Disease in Middle-Aged and Elderly Persons

作　　者：陈孟英[1] 张晶[1] 王伟[1] 梁蓉[1] 

机构地区：[1]天津市胸科医院心内科,300051

出　　处：《天津医药》2013年第8期776-778,共3页Tianjin Medical Journal

摘　　要：目的探讨中老年单纯收缩期正常高值血压患者发生冠心病的风险。方法选择236例接受冠状动脉造影检查的血压正常高值的中老年患者,按照血压水平分为单纯收缩期正常高值血压(ISHNBP)组135例和非单纯收缩期正常高值血压(NISHNBP)组101例,收集患者的临床和冠状动脉造影资料。结果 NISHNBP组和ISHNBP组收缩压比较差异无统计学意义(P>0.05),ISHNBP舒张压较低并且脉压较大,差异均有统计学意义(P<0.01)。多因素Logistic回归分析显示,单纯收缩期正常高值血压是冠心病的独立危险因素(OR=2.67,95%CI:1.50～4.75,P<0.01)。单纯收缩期正常高值血压组冠状动脉病变血管分布更广泛(P<0.01)。结论重视中老年单纯收缩期正常高值血压患者的冠心病风险并加以适当的干预,可能有助于降低心脑血管疾病的发生率。Objective To investigate the relationship between isolated systolic high-normal blood pressure and cor- onary heart disease {CI-ID） in the middle-aged and elderly population. Methods A total of 236 patients over 50 years old and undergone coronary angiography were enrolled and divided into isolated systolic high-normal blood pressure （ISHNBP） group （n=135） and non-ISHNBP （NISHNBP） group （n=101） according to their systolic and diastolic blood pressure levels. All clinical data and angiographic data were collected. Results There was no significant difference in systolic blood pres- sure between NISHNBP group and ISHNBP group （P 〉 0.05）. There were significantly lower levels of diastolic blood pres- sure and higher pulse pressure in ISHNBP group （P 〈 0.01）. Results of multivariate logistic analysis showed that isolated sys- tolic high-normal blood pressure was the independent risk factor for CHD （OR=2.67,95%CI：1.50-4.75, P 〈 0.01）. And the distribution of diseased coronary vessel numbers was more extensive in the ISHNBP group （P 〈 0.01）. Conclusion The iso- lated systolic blood pressure in the middle-aged and elderly population with high risk of coronary heart disease should be paid attention to, and make appropriate interventions, which may help reduce the incidence of cardiovascular disease.

关 键 词：高血压 心肌收缩 心舒期 冠心病 正常高值血压 

分 类 号：R544.1[医药卫生—心血管疾病]