肝脏移植术后自身免疫性溶血性贫血:附3例报告  

Autoimmune hemolytic anemia after orthotopic liver transplantation:analysis of 3 cases

作　　者：傅卫军[1] 陈辉[1] 徐建设[2] 王慧[2] 陈仲清[1] 王瑞婷[1] 

机构地区：[1]南方医科大学南方医院重症医学科,广东广州510515 [2]南方医科大学南方医院麻醉科,广东广州510515

出　　处：《南方医科大学学报》2013年第8期1240-1242,1249,共4页Journal of Southern Medical University

基　　金：广东省医学科学技术研究基金(A2013366)

摘　　要：目的分析肝脏移植术后自身免疫性溶血性贫血的诊断和治疗方法。方法回顾肝脏移植后发生自身免疫性溶血性贫血的3例患者的诊断及治疗前后的溶血象检查,血红蛋白、白细胞、血小板、总胆红素和谷丙转氨酶的变化趋势。结果 3例患者均出现与免疫抑制剂可能相关的自身免疫性溶血性贫血,经过治疗后均得到有效控制。结论肝脏移植后自身免疫性溶血性贫血是肝脏移植后少见并发症之一,明确其诊断后进行针对性治疗,可成功治愈。Objective To analyze the diagnosis and treatment of autoimmune hemolytic anemia(AIHA) in liver transplant recipients.Methods A retrospective analysis was conducted of 3 patients who developed AIHA following orthotopic liver transplantation.The results of hemolysis tests and examinations of hemoglobin,white blood cells,platelets,total bilirubin,and alanine aminotransferase before and after treatments were reviewed.Results These 3 patients developed AIHA following the transplantation possibly in association with the use of immunosuppressive agents,and the condition was effectively controlled after corresponding treatments.Conclusion AIHA is a uncommon complication after liver transplantation and can be cured after a definitive diagnosis with corresponding treatments.

关 键 词：自身免疫性溶血性贫血 肝脏移植 免疫抑制剂 

分 类 号：R657.3[医药卫生—外科学]