刺血拔罐对带状疱疹后遗神经痛患者血清P物质的影响  

Impacts of bleeding and cupping therapy on serum P substance in patients of postherpetic neuralgia

作　　者：田浩[1] 田永静[2] 王兵[1] 杨莉[1] 王莹莹[1] 杨金生[1] 

机构地区：[1]中国中医科学院针灸研究所,北京100700 [2]首都医科大学附属北京朝阳医院

出　　处：《中国针灸》2013年第8期678-681,共4页Chinese Acupuncture & Moxibustion

基　　金：国家自然科学基金项目:81173346

摘　　要：目的:观察刺血拔罐治疗带状疱疹后遗神经痛的疗效,并对其镇痛机制进行初步探讨。方法:将64例带状疱疹后遗神经痛患者随机分为两组,每组32例。刺血拔罐组:于患者疼痛局部采用注射针点刺及负压拔罐器拔罐治疗,隔日1次,治疗8次;普瑞巴林组:采用普瑞巴林口服治疗,150mg/次,每天2次,治疗16天。观察两组患者治疗前后视觉模拟量表(VAS)评分及外周与局部血清P物质含量变化。结果:两组治疗后VAS评分及外周血清P物质与治疗前比较均显著降低(均P<0.01),而刺血拔罐组降低更显著(P<0.01);刺血拔罐组治疗后局部血清P物质含量与治疗前比较显著降低[(93.86±9.87)pg/mL vs(46.13±6.31)pg/mL,P<0.01]。结论:刺血拔罐治疗带状疱疹后神经痛的疗效肯定,可显著降低患者外周及局部血清P物质含量,这可能是其发挥镇痛效应的机制之一。Objective To observe the effect of bleeding and cupping therapy on postherpetic neuralgia （PHN） and preliminarily discuss the analgesic mechanism. Methods Sixty-four cases of PHN were randomized into two groups, 32 cases in each one. In the bleeding and cupping group, the local pricking with syringe needle and cup- ping was applied in the local painful area, once every two days. And totally 8 treatments were required. In the pre- gabalin group, pregabalin was prescribed for oral administration, 150mg/time, twice a day. And totally 16 days of medication were required. Visual analogue scale （VAS） score and the changes of P substance content in the peripheral and local serum before and after treatment were observed in the two groups. Methods VAS score and peripheral serum P substance after treatment were lower significantly than those before treatment in the two groups （all P〈0.01）. The result in the bleeding and cupping group was much more significant （P〈0.01）. The local serum P substance after treatment was reduced significantly than that before treatment in the bleeding and cupping group [（93. 86529.87）pg/mL vs （46.13±6.31） pg/mL, P〈0.01]. Conclusion Bleeding and cupping therapy achieves the definite efficacy on PHN and it can reduce significantly peripheral and local serum P substance content in the patients. It is possibly one of the mechanisms of analgesic effect.

关 键 词：带状疱疹后遗神经痛 刺血疗法 拔罐疗法 P物质 

分 类 号：R246.7[医药卫生—针灸推拿学]