SARS CoV非自然起源  

Unnatural origin of SARS CoV

作　　者：徐德忠[1] 张磊[1] 孙慧敏[1] 于晓寒[1] 

机构地区：[1]第四军医大学军事预防医学院军队流行病学教研室,陕西西安710032

出　　处：《医学争鸣》2013年第4期6-9,共4页Negative

摘　　要：我们在国际上首次判明自然界根本不存在SARS CoV贮存宿主,其由Bt-SLCoV经"非自然(基因改造)"产生。此意味着人类已进入经"新型人工病毒"致全球性流行的时代。我们按透过现象看本质之思维,从SARS流行病学和临床特征明显反常这一事实,进一步阐明其非自然之起源:①流行早、中期广东省病例均在广州的西面和南面,而东面和北面无1例;②2003-12~2004-01,广州爆发4例,症状轻,无续发,均因SARS CoV在人群中逆向进化所致,随后在2004-03~04实验室爆发9例,亡1例,且极具超级传播性,与2002~2003年流行一致,未经逆向进化;③作为特定传染源——受染果子狸仅在深圳和广州2个动物市场,可为非自然引入所乘。故人类正面临空前威胁,应群起应对。We have first illuminated in our recent article that SARS CoV was born ＂＇unnaturally （gene modified）＂ from Bt-SLCoV. without its reservoir in nature. This means that mankind has entered the era of the global epidemic caused by the ＂＇new type of the virus＂, i.e., ＂＇the artificial virus＂. With the idea of＂see through the appearance to perceive the essence＂, we furthcr clarify＂ the unnatural origin of SARS CoV according to very unusual epidemiological and clinical characteristics of SARS in the paper, （1） The cases of Guangdong province in early and middle epidemic phases were all in the west and south of Guangzhou city, and none in the east and north. （2） There was no secondary case following the tour cases with mild clinical manifestations in Guangzhou outbreak l^om December 2003 to January 2004. because SARS CoV had experienced reverse evolution in human population; whereas, subsequently between March and April of 2004, one of nine cases died in the laboratory outbreak with super-spreader, just like the epidemic of 2002-2003 caused by the virus without reverse evolution. （3） As the specific source of infection, the infected civets were found only in two live-animal markets of Shcnzhen and Guangzhou, which was the best opportunity for SARS CoV unnatural introduction. So we all should together protect ourselves from the unprecedented threaten in the world.

关 键 词：SARS冠状病毒 流行病学 逆向进化 活动物市场 基因改造 

分 类 号：R18[医药卫生—流行病学]