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机构地区:[1]成都军区总医院消化内镜中心,成都610083 [2]泸州医学院2011级消化内科
出 处:《西南国防医药》2013年第8期848-850,共3页Medical Journal of National Defending Forces in Southwest China
摘 要:目的研究不明原因小肠出血胶囊内镜检查术前准备,力图寻找一种较为理想的术前方法,提高疾病的检出率。方法选取2009年7月~2012年6月,因消化道出血就诊、胃肠镜检查未明确诊断的62例患者,随机分为3组。A组(复方聚乙二醇电解质散)19例、B组(在A组的基础上联合二甲硅油散)21例、C组(在B组的基础上联合莫沙必利分散片)22例。观察胶囊内镜通过幽门时间、小肠检查完成率、图像采集质量(气泡量、消化液量、消化液清洁度以及整体观察效果)、病变检出情况、胶囊内镜术前肠道准备安全性等指标。结果胶囊内镜通过幽门时问C组短于A、B组(P〈0.05),全小肠检查完成率C组高于A和B组(P〈0.05),气泡量A组较B、C组多(P〈0.05),消化液量C组较A、B组减少(P〈0.05),消化液清洁度c组较A、B组更为清晰(P〈0.05)。整体观察效果,C组无任何干扰并优于A、B组,c组病变检出率高于A、B组(P〈0.05),A组有1例未完成检查;胶囊内镜术前肠道准备安全性3组间无明显差异。结论在胶囊内镜术前服用促胃肠动力的药物,可缩短胶囊内镜通过幽门时间,提高全小肠检查完成率;术前服用消泡剂,可以减少肠道中的气泡量;复方聚乙二醇电解质散联合二甲硅油散和莫沙必利分散片,祛泡效果佳、清洁度强、耐受安全性好,提高了不明原因消化道出血疾病的检出率,是较理想的胶囊内镜术前准备方法。Objective To explore the preoperative preparation method of capsule endoscopy for agnogenic small intestinal hemorrhage in order to find out an ideal preoperative method to increase the detection rate of diseases. Methods Between July 2009 and June 2012, there were 62 patients with alimentary tract hemorrhage who were not clearly diagnosed by gastrointestinal endoscopy. They were randomly divided into 3 groups. There were 19 cases in group A (compound polyethylene glycol electrolyte powder) ,21 ones in group B ( dimethicone powder was used based on the treatment of group A) , and 22 ones in group C ( mosapride dispersible tablet was used based on the treatment of group B ). Observation was made in the transit time of capsule endoscopy through the pylorus, the completion rate of small intestine examination, the quality of image acquisition ( the amount of bubbles, digestive fluid volume, the cleaness of digestive fluid, and the overall observation effect) , the lesion detection, and the safety of bowel preparation before capsule endoscopy. Results The transit time of capsule endoscopy through the pylorus in group C was shorter than that in group B and A ( P 〈 0.05 ). The completion rate of small intestine examination in group C was higher than that in group A and B ( P 〈0. 05 ). The amount of bubbles in group A was more than group B and C ( P 〈 0. 05 ). The digestive fluid volume in group C decreased compared with that in group A and B ( P 〈 0.05 ). The cleaness of digestive fluid was clearer than that in group A and B ( P 〈 0.05 ). The overall observation effect in group C had no interference and was superior to that in group A and B. The lesion detection rate of group C was higher than that of group A and B ( P 〈 0.05 ). There was 1 case that did no complete the examination. There was no significant difference in the safety of bowel preparation before the capsule endoscopy among the three groups. Conclusion Taking drugs of promoting gastrointestinal motility be
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